Ameloblastic fibro-odontoma (AFO) is a slow-growing, expansive, benign odontogenic tumor, composed of ameloblastic epithelium embedded in an ectomesenchymal stroma resembling dental papilla, containing hard dental tissue in variable degrees of maturation, including enamel, dentin, and sometimes cementum. AFO typically affects the posterior mandible, causing bony expansion. We report a case of pigmented AFO in a 5-year-old boy, comprising clinical and histological features illustrated by immunohistochemistry using a large panel of antibodies, polarized light microscopy and scanning electron microscopy.
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Article Synopsis
- The terminology used to describe developmental lesions in the oral cavity can be confusing, particularly in distinguishing between developmental malformations and neoplasia, especially in odontogenic tumors.
- The report discusses the definitions of malformations and neoplasia, highlighting their significance within the context of odontogenic tumors.
- Understanding these concepts is crucial for accurately classifying and treating mixed odontogenic lesions.
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