Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/pme.12573 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Total neoadjuvant therapy followed by total mesorectal excision for rectal cancer in older patients real world data and proof of concept.
Front Surg
November 2024
General Surgery Unit, Ospedale Santa Maria Delle Croci - AUSL Romagna, Ravenna, Italy.
Background: Rectal cancer (RC) commonly affects older patients. Total Neoadjuvant Therapy (TNT) has been introduced to improve local and systemic control of RC. The aim was to present real-world data of older patients receiving TNT followed by surgery after a frailty assessment and verify feasibility and safety of this approach.
View Article and Find Full Text PDFArticle Synopsis
- This study analyzes the response of the Brazilian ionosphere to geomagnetic storms driven by Corotating Interaction Regions (CIR) and High-Speed Solar Wind Streams (HSS) during 2016-2017.
- It investigates Vertical Total Electron Content (VTEC) variations across three regions: equatorial, northern crest, and southern crest of the Equatorial Ionization Anomaly, noting both enhancements and depletions of up to 30 and 20 TECu, respectively.
- The research also highlights the timing of these variations, the role of electric fields in the ionosphere, and includes new catalogs for low-latitude ionospheric storms useful for space weather and modeling.
Bayesian modeling for analyzing heterogeneous response in preclinical mouse tumor models.
Sci Transl Med
October 2024
Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA UK.
In anticancer research, tumor growth measured in mouse models is important for assessing treatment efficacy for a treatment to progress to human clinical trials. Statistical analysis of time-to-event tumor volume data is complex because of heterogeneity in response and welfare-related data loss. Traditional statistical methods of testing the mean difference between groups are not robust because they assume common responses across a population.
View Article and Find Full Text PDFGDF-15 levels in patients with polycystic ovary syndrome treated with metformin: a combined clinical and in silico pathway analysis.
Arch Endocrinol Metab
October 2024
Faculdade de Farmácia Universidade Federal de Minas Gerais Belo HorizonteMG Brasil Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
Article Synopsis
- - The study investigates the connection between growth and differentiation factor 15 (GDF-15) levels and polycystic ovary syndrome (PCOS), finding that GDF-15 is higher in women with PCOS compared to controls.
- - Among women with PCOS, those treated with metformin showed significantly increased GDF-15 levels compared to those on a placebo.
- - The research indicates that GDF-15 may play a role in various biological pathways associated with PCOS, including hormonal responses and metabolic processes.
Perceptual training with implicit and explicit learning improves the prediction of ball direction in soccer penalty kicks.
Int J Psychol
December 2024
Department of Physical Education, Motor Neuroscience Laboratory, Londrina State University, Londrina, Brazil.
Perceptual training enhances the ability to anticipate crucial information for decision-making, for example, a soccer goalkeeper predicting penalty kick direction. However, it remains unclear whether perceptual practice alone (implicit method) is sufficient for optimal decision-making improvement, or whether emphasising pertinent details during practice (explicit method) could yield better results. This study compared implicit and explicit methods of learning ball direction prediction during soccer penalties, involving both goalkeepers and non-soccer players (novices).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!