1. In the course of an experiment in which acute effects of perorally applied ethanol alone (0.5 g/kg of body weight) or in combination with diazepam (5 mg) and meclophenoxate (100 mg) on verbal learning were studied, the values of the blood pressure, the body temperature and the heart rate of experimental subject were simultaneously registered with the help of polyphysiograph Physiomat. 2. The method of artificial conditioned speech connections was adopted. The experimental subjects were 16 healthy and unfatigued volunteers - university students (8 females, 8 males, age 21 years). The investigation-sets consisted of two optic, two complex tactile, and two acoustic associations. Three trials were always carried out: before, and one and two hours after the administration of the studied drugs. 3. The values of the blood pressure, the body temperature and the heart rate were not significantly influenced by the applied substances. Only two hours after application of ethanol in combination with diazepam, a marked decrease of systolic and diastolic blood pressure was registered in comparison with the values observed after application of placebo.
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Int J Surg
January 2025
Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, SAR.
Background: Understanding based on up-to-date data on the burden of non-communicable diseases (NCDs) is limited, especially regarding how subtypes contribute to the overall NCD burden and the attributable risk factors across locations and subtypes. We aimed to report the global, regional, and national burden of NCDs, subtypes, and attributable risk factors in 2021, and trends from 1990 to 2021 by age, sex, and socio-demographic index (SDI).
Materials And Methods: We used data from the Global Burden of Disease Study 2021 to estimate the prevalence, deaths, and disability-adjusted life years (DALYs) for NCDs and subtypes, along with attributable risk factors.
Sleep Breath
January 2025
Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland.
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Methods: Fifteen patients mild, moderate or severe OSA and concomitant bradycardia were enrolled.
Alzheimers Dement
January 2025
Department of Public and Occupational Health, Amsterdam UMC Location VUMC, Amsterdam, the Netherlands.
Introduction: We explored which dementia risk factors in two multidomain prevention trials mediate beneficial, neutral, or counteracting effects on dementia incidence.
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Artif Organs
January 2025
Division of Life Science and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei, China.
Background: Membrane oxygenators facilitate extracorporeal gas exchange, necessitating the monitoring of blood gas. Recent advances in normothermic machine perfusion (NMP) for ex vivo liver offer solutions to the shortage of donor liver. However, maintaining physiological blood gas levels during prolonged NMP is complex and costly.
View Article and Find Full Text PDFJ Gerontol B Psychol Sci Soc Sci
January 2025
Department of Medicine, Health, and Society, Vanderbilt University, Nashville, Tennessee, USA.
Objectives: Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) older adults have varied experiences with faith communities, ranging from affirmation to religious trauma. We investigate how faith community rejection impacts social support and health outcomes among LGBTQ+ older adults in the Southern United States.
Methods: We analyze Wave 1 data from the LGBTQ+ Social Networks, Aging, and Policy Study (QSNAPS), collected between April 2020 and September 2021.
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