Cancer remains a lethal disease, and many scientists are currently trying to develop more effective therapies. Natural compounds are potential sources of anti-cancer therapies and are obtained from diverse sources including marine organisms, microorganisms and plants. In this paper, we evaluated natural compounds from non-edible plant sources, which is a neglected area of research despite the promising future of these compounds. In addition, we assessed the function and mechanism of action of these compounds in relation to cancer chemoprevention.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189471 | PMC |
http://dx.doi.org/10.15430/jcp.2014.19.1.1 | DOI Listing |
Sci Rep
December 2024
Sustainability Solutions Research Lab, Faculty of Engineering, University of Pannonia, Egyetem Str. 10, Veszprém, 8200, Hungary.
Ensuring everyone enjoys healthy lifestyles and well-being at all ages, Progress has been made in increasing access to clean water and sanitation facilities and reducing the spread of epidemics and diseases. The synthesis of nano-particles (NPs) by using microalgae is a new nanobiotechnology due to the use of the biomolecular (corona) of microalgae as a capping and reducing agent for NP creation. This investigation explores the capacity of a distinct indigenous microalgal strain to synthesize silver nano-particles (AgNPs), as well as its effectiveness against multi-drug resistant (MDR) bacteria and its ability to degrade Azo dye (Methyl Red) in wastewater.
View Article and Find Full Text PDFNat Commun
December 2024
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Polychlorinated naphthalenes (PCNs) are persistent organic compounds that are regulated by the Stockholm Convention. Here, we estimate historical emissions from PCN production and use (1912-1987) and unintentional emissions from 20 categories (2000-2020). A random forest regression model projects emissions for 2020-2050.
View Article and Find Full Text PDFNat Commun
December 2024
PSI Center for Life Sciences, Villigen PSI, Switzerland.
G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in humans. The binding and dissociation of ligands tunes the inherent conformational flexibility of these important drug targets towards distinct functional states. Here we show how to trigger and resolve protein-ligand interaction dynamics within the human adenosine A receptor.
View Article and Find Full Text PDFNat Commun
December 2024
Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Key Laboratory of Physical Oceanography, Ministry of Education, the College of Oceanic and Atmospheric Sciences, Ocean University of China, and Laoshan Laboratory, Qingdao, China.
A shift in depth range enables marine organisms to adapt to marine heatwaves (MHWs). Subsurface MHWs could limit this pathway, yet their response to climate warming remains unclear. Here, using an eddy-resolving Earth system model forced under a high emission scenario, we project a robust global increase in subsurface MHWs driven by rising subsurface mean temperatures and enhanced temperature variability.
View Article and Find Full Text PDFZ Naturforsch C J Biosci
January 2025
Laboratory of Molecular Chemistry and Natural Substances, Faculty of Sciences of Meknes, 11201 Zitoune-Meknes B.P, Meknes, Meknes, Morocco.
In order to search for new chemotypes and to carry out a comparative study with the literature, the current study investigated the chemical composition of the essential oil of the flowers of (L.) ssp. using gas chromatography coupled with mass spectrometry (GC-MS).
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