Altered self-perception in adult survivors treated for a CNS tumor in childhood or adolescence: population-based outcomes compared with the general population.

Neuro Oncol

Childhood Cancer Research Unit, Karolinska Institutet, Astrid Lindgren Children's Hospital Q6:05, Stockholm, Sweden (L.H., J.R., G.G., K.K.B.); Department of Psychology, Stockholm University, Stockholm, Sweden (J.R.); Department of Clinical Sciences, Department of Pediatrics, The Queen Silvia Children's Hospital, University of Gothenburg, Gothenburg, Sweden (B.L.).

Published: May 2015

AI Article Synopsis

  • Survivors of pediatric CNS tumors face long-term challenges in self-perception, impacting their mental health and overall quality of life.
  • A study involving 697 Swedish survivors found that they reported significantly poorer self-perception in areas like body image, work, and social relationships compared to the general population.
  • Factors such as female gender and visible physical effects from treatment were linked to worse self-perception outcomes, emphasizing the need for psychological support in their ongoing care.

Article Abstract

Background: Survivors of pediatric CNS tumors are at risk for persistent tumor/treatment-related morbidity, physical disability and social consequences that may alter self-perception, vital for self-identity, mental health and quality of survival. We studied the long-term impact of childhood CNS tumors and their treatment on the self-perception of adult survivors and compared outcomes with those of the general population.

Methods: The cohort included 697 Swedish survivors diagnosed with a primary CNS tumor during 1982-2001. Comparison data were randomly collected from a stratified general population sample. Survivors and general population individuals were compared as regards self-perception in 5 domains: body image, sports/physical activities, peers, work, and family, and with a global self-esteem index. Within the survivor group, determinants of impact on self-perception were identified.

Results: The final analyzed sample included 528 survivors, 75.8% of the entire national cohort. The control sample consisted of 995, 41% of 2500 addressed. Survivors had significantly poorer self-perception outcomes in domains of peers, work, body image, and sports/physical activities, and in the global self-perception measure, compared with those of the general population (all P < .001). Within the survivor group, female gender and persistent visible physical sequelae predicted poorer outcomes in several of the studied domains. Tumor type and a history of cranial radiation therapy were associated with outcomes.

Conclusion: An altered self-perception is a potential late effect in adult survivors of pediatric CNS tumors. Self-perception and self-esteem are significant elements of identity, mental health and quality of survival. Therefore, care and psychosocial follow-up of survivors should include measures for identifying disturbances and for assessing the need for psychosocial intervention.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482851PMC
http://dx.doi.org/10.1093/neuonc/nou289DOI Listing

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