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Background And Aim: Managing benign biliary stricture endoscopically is complicated and challenging. This study aimed to evaluate the safety and efficacy of a 6-month placement of a fully covered self-expanding metallic stent for refractory benign biliary stricture.
Methods: Twenty-two patients with refractory benign biliary stricture (13 with chronic pancreatitis and 9 without) were recruited from five higher tertiary care centers.
Explant pathology in Biliary Atresia post Kasai procedure: a tale of two livers.
Autops Case Rep
October 2024
Sir Ganga Ram Hospital, Pediatric Gastroenterology and Hepatology, New Delhi, India.
Article Synopsis
- - Biliary atresia (BA) is a severe liver condition in infants that causes inflammation and blockage of bile ducts, leading to cirrhosis within two years if untreated.
- - Early diagnosis is crucial, and the best initial treatment is the Kasai procedure, which should be performed within the first two months of life to maximize the chances of success.
- - The outcomes of the Kasai procedure vary, with potential long-term complications requiring liver transplant; pathologists need to differentiate between various liver damage patterns in successful versus failed surgeries for accurate diagnosis.
Tubulointerstitial nephritis with IgM-positive plasma cells complicated by liver failure.
CEN Case Rep
October 2024
Department of Rheumatology, Endocrinology, and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 14, Nishi 5, Kita-ku, Sapporo, 060-8648, Japan.
Article Synopsis
- Tubulointerstitial nephritis (TIN) is an inflammation of the kidney interstitium, often involving T cells, with a newer classification called IgMPC-TIN characterized by IgM-positive plasma cell infiltration.
- A 70-year-old woman with Fanconi syndrome and renal tubular acidosis was diagnosed with IgMPC-TIN, showing improvement in renal function after corticosteroid treatment, but ultimately died from liver failure and complications.
- The autopsy findings indicated liver issues such as nodular regenerative hyperplasia, suggesting that IgMPC-TIN can also manifest in liver diseases, expanding its known associations beyond just primary biliary cholangitis (PBC).
Clinically significant portal hypertension in patients with primary biliary cholangitis: Clinicopathological features and prognostic value.
Ann Hepatol
September 2024
Department of Hepatology, Hepatology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian Province, PR China; Department of Hepatology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, Fujian Province, PR China. Electronic address:
Introduction And Objectives: Primary biliary cholangitis (PBC) may progress to clinically significant portal hypertension (CSPH) before the development of cirrhosis. This study aimed to investigate CSPH incidence as well as the clinicopathological characteristics and predictive value of these features for the prognosis of patients with PBC, especially at early histologic stage.
Patients And Methods: Patients diagnosed with PBC between January 2013 and April 2022 were retrospectively enrolled.
Vanek's Tumour as a Rare Cause of Dyspeptic Syndrome in a Patient with Primary Biliary Cholangitis: A Case Report.
Rev Recent Clin Trials
October 2024
Hepatogastroenterology Division, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Via Luigi de Crecchio, Naples, 80138, Italy.
Background: Inflammatory Fibroid Polyp (IFP), also known as Vanek's tumour, is a rare mesenchymal gastrointestinal tumour, potentially causing a wide range of clinical manifestations (even though it can be completely asymptomatic) primarily related to the location of the formation. The available evidence suggests a fundamentally non-neoplastic behaviour of IFP.
Case Presentation: A 67-year-old female was presented with persistent dyspepsia despite symptomatic therapy.
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