AI Article Synopsis
- Microglia are specialized immune cells in the brain that become increasingly important in understanding brain health and diseases.
- When faced with even slight damage, microglia can become overactive, releasing inflammatory substances that can lead to neuroinflammation and various neurological disorders.
- The review focuses on recent research findings that highlight microglia's significant role in a range of brain-related diseases.
Article Abstract
At the frontier between immunology and neuroscience, microglia, the enigmatic macrophages of the brain, have generated, in recent years, increasing interest. In response to even minor pathological changes in the brain, these extremely versatile glial cells occasionally enter in an over-activating state and produce pro-inflammatory cytokines and free radicals, thereby contributing directly to neuroinflammation and various brain disorders. This review provides an analysis of the latest developments in the microglia field, considering the important new research that illustrate their involvement in brain related diseases.
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