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Clear cell myoepithelioma of palate: A rare case report with brief review of literature.
J Oral Maxillofac Pathol
October 2024
Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y.Patil Vidyapeeth, Pune, Maharashtra, India.
Myoepitheliomas are very rare salivary gland neoplasms seen mainly in the major salivary glands (~40%) followed by minor salivary glands (~21%). Palatal myoepitheliomas are rare, with clear cell types being even rarer. Due to the rarity of this tumor, it lacks specific features that are diagnostic in cytology.
View Article and Find Full Text PDFMyoepithelioma Arising in the Buccal Mucosa: A Case Report and Review of the Literature.
Cureus
November 2024
Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, JPN.
Although myoepithelioma is defined as a benign tumour made up primarily of neoplastic myoepithelial cells, its actual histopathological characteristics are highly diverse. It can be considered a rare disease. The most common site of occurrence is the parotid gland, followed by the minor salivary glands of the palate.
View Article and Find Full Text PDFA Rare Presentation of Myoepithelioma of the Parotid Gland Manifesting as an Infra-Auricular Swelling.
Cureus
October 2024
Department of Otolaryngology, Head and Neck Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Article Synopsis
- The report discusses myoepithelioma, an uncommon tumor of the salivary glands, particularly affecting the parotid gland, and typically considered benign.
- Myoepitheliomas arise from abnormal growth of myoepithelial cells and are classified as a type of pleomorphic adenoma, making their diagnosis challenging due to their complex characteristics.
- A case of a 42-year-old woman with a lump in the right infra-auricular area is presented, where initial assessments suggested an oncocytic lesion, but further tests confirmed it was a myoepithelioma in the parotid gland.
DNA Methylation Profiling of Salivary Gland Tumors Supports and Expands Conventional Classification.
Mod Pathol
December 2024
DERMPATH München, Munich, Germany.
Article Synopsis
- Tumors of salivary glands vary widely and can overlap, making them challenging to diagnose, despite advances in molecular testing.
- A study examined 363 cases of 20 different salivary gland tumors and found distinct DNA methylation patterns that help classify these tumors, achieving high accuracy with a machine learning algorithm.
- The research identified specific epigenetic signatures, distinguishing certain tumor types, and suggested that DNA methylation could aid in diagnosing and potentially uncovering new tumor classes in the future.
Unveiling rarity: Myoepithelioma in the minor salivary gland of buccal mucosa - A case report.
Int J Surg Case Rep
July 2024
Oral and Maxillofacial Surgeon, Pune, Maharashtra, India.
Introduction: Tumours of salivary glands are rare and have various histo-pathological subtypes. Myoepitheliomas were first classified by Sheldon et al. and the criterion to classify or diagnose it was first defined by Barnes et al.
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