Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/etc.2714 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Improved Mesenchymal Stem Cell Viability in High-Stiffness, Translational Cartilage Matrix Hydrogels.
Tissue Eng Part A
January 2025
C. Wayne McIlwraith Translational Medicine Institute, Colorado State University, Fort Collins, Colorado, USA.
Scaffolds made from cartilage extracellular matrix are promising materials for articular cartilage repair, attributed to their intrinsic bioactivity that may promote chondrogenesis. While several cartilage matrix-based scaffolds have supported chondrogenesis and/or , it remains a challenge to balance the biological response (e.g.
View Article and Find Full Text PDFRobust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity.
Elife
January 2025
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, United States.
Single-nucleus RNA sequencing (snRNA-seq), an alternative to single-cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering its applications. Here, we present a robust technique for isolating nuclei across various tissue types, remarkably enhancing snRNA-seq data quality. Employing this approach, we comprehensively characterize the depot-dependent cellular dynamics of various cell types underlying mouse adipose tissue remodeling during obesity.
View Article and Find Full Text PDFUrban River Policies: Multilevel Analysis and Community Engagement in Curitiba.
Environ Manage
January 2025
Graduate Program in Urban Management (PPGTU), Center for Studies in Urban Policies (CE.URB), Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Paraná, Brazil.
This study investigates urban river policies, emphasizing the gaps in understanding the interactions between riverine communities and governance systems. Using empirical and theoretical methods, the research applies multivariate analysis and Structural Equation Modeling (SEM) to data from a representative sample of 1740 residents of Curitiba. The study maintains a 95% confidence level with a ±2.
View Article and Find Full Text PDFThe structure and motivational significance of early beliefs about ability.
Dev Psychol
January 2025
Department of Psychology, New York University.
Adults hold a broad range of beliefs about intellectual ability. Key examples include beliefs about its malleability, its distribution in the population, whether high levels of it ("brilliance") are necessary for success, its origins, and its responsiveness to intervention. Here, we examined the structure and motivational significance of this network of consequential beliefs in a sample of elementary school-age children (5- to 11-year-olds, = 231; 116 girls, 112 boys, three gender nonbinary children; predominantly White and Asian children from relatively high-income backgrounds).
View Article and Find Full Text PDFRisankizumab Efficacy and Safety Based on Prior Inadequate Response or Intolerance to Advanced Therapy: Post Hoc Analysis of the INSPIRE and COMMAND Phase 3 Studies.
J Crohns Colitis
January 2025
Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Background And Aims: Treating ulcerative colitis (UC) in patients with prior advanced therapy (AT) exposure may be challenging. We report the efficacy and safety of risankizumab, a monoclonal interleukin 23p19 antibody, in patients with UC and prior inadequate response or intolerance to AT (AT-IR).
Methods: In the 12-week phase 3 INSPIRE induction study, patients were randomized to intravenous risankizumab 1200 mg or placebo.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!