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http://dx.doi.org/10.1097/CCM.0000000000000589 | DOI Listing |
JAMA Netw Open
December 2024
Influenza Division, National Center for Immunization and Respiratory Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia.
Importance: Increasing the understanding of vaccine effectiveness (VE) against levels of severe influenza in children could help increase uptake of influenza vaccination and strengthen vaccine policies globally.
Objective: To investigate VE in children by severity of influenza illness.
Design, Setting, And Participants: This case-control study with a test-negative design used data from 8 participating medical centers located in geographically different US states in the New Vaccine Surveillance Network from November 6, 2015, through April 8, 2020.
Influenza Other Respir Viruses
December 2024
Ministry of Health and Population, Cairo, Egypt.
Introduction: Influenza burden (IB) estimates are crucial for monitoring disease trends, allocating limited resources, and promoting influenza vaccination. However, IB in Egypt is poorly understood. This study estimates the mean-seasonal IB in Egypt, across levels of severity by age and regions using sentinel surveillance data between 2016 and 2019.
View Article and Find Full Text PDFMediators Inflamm
December 2024
Emergency Department, Henan Province Engineering Research Center of Diagnosis and Treatment of Pediatric Infection and Critical Care, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
This study aims to investigate the predictive value of interleukin-6 (IL-6) and lymphocyte subsets for death in children with influenza-associated encephalopathy (IAE). This study included 76 children with IAE who were divided into a death group and a survival group. The differences in the levels of IL-6 and lymphocyte subsets between the two groups were analyzed, and the predictive value of these two parameters was compared by receiver operating characteristic (ROC) curve analysis.
View Article and Find Full Text PDFmedRxiv
October 2024
Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Problem/condition: Seasonal influenza accounts for 9.3 million-41 million illnesses, 100,000-710,000 hospitalizations, and 4,900-51,000 deaths annually in the United States. Since 2003, the Influenza Hospitalization Surveillance Network (FluSurv-NET) has been conducting population-based surveillance for laboratory-confirmed influenza-associated hospitalizations in the United States, including weekly rate estimations and descriptions of clinical characteristics and outcomes for hospitalized patients.
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