Anorectal malformations and Down syndrome.

Am J Med Genet

Department of Human Genetics, Hadassah Hospital Ein Karem, Hebrew University Hadassah Medical School, Jerusalem, Israel.

Published: November 1989

AI Article Synopsis

  • A study conducted in Jerusalem from 1980 to 1986 identified 89 children with Down syndrome and 42 with imperforate anus among 64,870 liveborn infants in the Jewish community.
  • Notably, two children had both conditions, highlighting a potential overlap between Down syndrome and imperforate anus.
  • The data reveals a significant incidence rate of imperforate anus (2.2%) among children diagnosed with Down syndrome in this population.

Article Abstract

During 1980 to 1986, 89 children with Down syndrome and 42 with imperforate anus were diagnosed among 64,870 liveborn infants in the Jewish population of Jerusalem. Two of the children had both Down syndrome and imperforate anus. This indicates a high incidence of imperforate anus among children with Down syndrome (2.2%).

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Source
http://dx.doi.org/10.1002/ajmg.1320340307DOI Listing

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