Objective: The aim of this study was to determine the prevalence of incidental ascending aortic dilation and its significance over time in 55- to 80-year-olds undergoing routine computed tomographic scans.
Methods: Chest computed tomography reports for 64,092 patients who met the inclusion criteria were used to determine the prevalence of incidental ascending aortic dilation (4-5 cm) and, when possible, aortic growth rates. A chart review was performed to identify any aortic complication or intervention.
Results: The prevalence of incidental aortic dilation was 2.7% (671/24,992 patients). Of the 327 patients with aortic dilation and follow-up studies (mean, 3.4 years), only 3.7% (n = 12) demonstrated interval growth (mean of 0.9 mm/y). No patient underwent prophylactic surgery or intervention on the basis of aortic size or growth rate. One patient developed a type A dissection.
Conclusions: Current guidelines for yearly surveillance imaging of aortic dilation could be revised to increase the follow-up interval and/or improve risk stratification to better identify the small subset of patients most likely to have disease progression.
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http://dx.doi.org/10.1097/RCT.0000000000000167 | DOI Listing |
Pediatr Cardiol
January 2025
Department of Cardiac Surgery, University Hospital of Gent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Restenosis occurs commonly after aortic coarctation (CoA) repair, usually requiring treatment by balloon dilation. Its effect on physical exercise performance is not documented. A retrospective analysis of exercise testing and echocardiographic assessment was performed in children after CoA repair.
View Article and Find Full Text PDFJ Cell Mol Med
January 2025
State Key Laboratory of Frigid Zone Cardiovascular Diseases, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Abdominal aortic aneurysm (AAA) is the most prevalent dilated arterial aneurysm that poses a significant threat to older adults, but the molecular mechanisms linking senescence to AAA progression remain poorly understood. This study aims to identify cellular senescence-related genes (SRGs) implicated in AAA development and assess their potential as therapeutic targets. Four hundred and twenty-nine differentially expressed genes (DEGs) were identified from the GSE57691 training set, and 867 SRGs were obtained.
View Article and Find Full Text PDFPediatr Res
January 2025
Faculty of Health Sciences, Joyce & Irving Goldman Medical School at Ben Gurion University of the Negev, Beer-Sheva, Israel.
Background: Coarctation of the aorta (CoA) is a narrowing of the aorta that affects 5-8% of congenital heart defects. Treatment options include surgical repair or transcatheter management with endovascular stenting or balloon dilatation. Late complications after operative repair include systemic hypertension, aortic valve abnormalities, aortic aneurysm, and recoarctation.
View Article and Find Full Text PDFPort J Card Thorac Vasc Surg
October 2024
Department of Vascular and Endovascular Surgery, St Francis Hospital & Heart Center, Roslyn, NY, USA.
The optimal management of acute type A aortic dissection (ATAAD) remains a controversial subject. While some surgeons opt for a hemiarch approach to minimize bypass and cross-clamping time, others prefer partial or total arch replacement to prevent the need for additional operations. The advent of hybrid approaches offers a variety of options to the aortic surgeon in treating ATAAD.
View Article and Find Full Text PDFPhysiol Meas
January 2025
Electronics, Universidad Favaloro, Solis 453, Buenos Aires, Buenos Aires, 1078, ARGENTINA.
Aortic dilatation is a severe pathology that increases the risk of rupture and its hemodynamics could be accurately assessed by using the 4D flow cardiovascular magnetic resonance (CMR) technique but flow assessment under complex flow patterns require validation. The aim of this work was to develop an in vitro system compatible with CMR to assess the accuracy of volume flow measurements in dilated aortas. Approach.
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