It is established that utilization of pond's acid tar and n-butyl-acrylate vat residue for the binding roadway covering composition and its further application are associated with the release of a significant amount of noxious substances into the air of the work zone and inhabited areas. A set of activities, directed at the reduction of negative influence of the given technology on the sanitary state of the workplace and community air has been developed.
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Cien Saude Colet
December 2024
Instituto Aggeu Magalhães - Fiocruz Pernambuco. Recife PE Brasil.
This article aims to characterize Indigenous people aged 18-23 of the Xukuru do Ororubá ethnic group, Pernambuco state, Brazil, regarding the use of dental services, self-perceived oral health, oral hygiene practices and caries experience, and socioeconomic and demographic aspects. This population-based cross-sectional study is nested in a cohort study that started in 2010 and was conducted in the Indigenous territory in 2018. Oral examinations and questionnaires were conducted with 131 Indigenous people.
View Article and Find Full Text PDFViruses
December 2024
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Vesicular stomatitis virus (VSV) represents a significant advancement in therapeutic medicine, offering unique molecular and cellular characteristics that make it exceptionally suitable for medical applications. The bullet-shaped morphology, RNA genome organization, and cytoplasmic replication strategy provide fundamental advantages for both vaccine development and oncolytic applications. VSV's interaction with host cells through the low-density lipoprotein receptor (LDL-R) and its sophisticated transcriptional regulation mechanisms enables precise control over therapeutic applications.
View Article and Find Full Text PDFViruses
November 2024
Laboratory for Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp (UA), Universiteitsplein 1 S.7, 2610 Antwerp, Belgium.
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in young children, elderly and immunocompromised patients worldwide. The RSV fusion (F) protein, which has 5-6 N-glycosylation sites depending on the strain, is a major target for vaccine development. Two to three of these sites are located in the p27 peptide, which is considered absent in virions.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Surgery, Semey Medical University, Semey 071400, Kazakhstan.
Cancer is a therapeutically challenging and genomically complicated disease. Pioneering studies have uncovered multifaceted aspects of cancer, ranging from intra- and inter-tumor heterogeneity, drug resistance, and genetic/epigenetic mutations. Loss of apoptosis is another critical aspect that makes cancer cells resistant to death.
View Article and Find Full Text PDFBehav Sci (Basel)
December 2024
Higher Education School, Polytechnic University of Coimbra, Rua da Misericórdia, Lagar dos Cortiços, S. Martinho do Bispo, 3045-093 Coimbra, Portugal.
Fitness instructors play an essential role in fitness services, as they require both technical and interpersonal skills. A good image of a fitness instructor can be defined as having a pleasant appearance and good presentation in terms of hygiene and/or clothing used, which is appropriate for the context and characteristics of the participants. Their image significantly influences participants' perceptions and satisfaction.
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