AI Article Synopsis
- The study aimed to evaluate the effectiveness of a standardized tool for detecting Chlamydia trachomatis in a family planning population, estimating its prevalence among consultations at an abortion center.
- The research involved a prospective observational study of 386 women, where a cervix sample was taken after a standardized questionnaire assessing clinical signs, and the samples were analyzed genetically.
- Results showed a 14.5% infection rate; the questionnaire was notably effective, particularly when all four clinical signs were present, but nearly half of the infected women displayed no clinical signs.
Article Abstract
Aim: To estimate the performance of a standardized interrogation tool facilitating the detection and screening of patients for the Chlamydia trachomatis infection, to estimate the prevalence of the infection in the family planning population studied.
Method: Prospective observational study, including the patients who had a consultation in the abortion center in the CHU of Poitiers. A sampling of the cervix was systematically carried out after the standardized interrogation in search of four clinical signs. The samples were analyzed by genetic amplification.
Results: Three hundred and eighty-six women were included and 56 (14.5 %) infections were identified. The medical history questionnaire was relatively effective for 2 or 3 clinical signs. The positive predictive value (PPV) was respectively 34.8 % and 53.8 % and was very relevant for 4 clinical signs with PPV at 83.3 % [CI 95 %: 74-93 %]. Among the infected women, 48.2 % had no clinical sign revealed by the medical history questionnaire. The presence of any clinical sign was strongly associated with the C. trachomatis infection (P<0.05).
Conclusion: The clinical signs find in the standardized interrogation are all significantly associated with the C. trachomatis infection.
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| http://dx.doi.org/10.1016/j.jgyn.2014.09.003 | DOI Listing |
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