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The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation.
Biochem Soc Trans
February 2022
School of Basic Sciences, Indian Institute of Technology Mandi, Mandi, Himachal Pradesh 175005, India.
Neuropeptides comprise a diverse and broad group of neurotransmitters in vertebrates and invertebrates, with critical roles in neuronal signal transduction. While their role in controlling learning and memory in the brains of mammals is known, their extra-synaptic function in infection and inflammation with effects on distinct tissues and immune cells is increasingly recognized. Helminth infections especially of the central nervous system (CNS), such as neurocysticercosis, induce neuropeptide production by both host and helminth, but their role in host-parasite interplay or host inflammatory response is unclear.
View Article and Find Full Text PDFNeurocysticercosis in a Japanese woman with lung cancer who repeatedly visited endemic countries.
BMC Infect Dis
October 2021
Department of Neurosurgery, Tokushima Municipal Hospital, 2-34, Kitajyosanjima-cho, Tokushima, 770-0812, Japan.
Background: Taenia solium, present in most developing countries, infects many individuals and may result in their death. Neurocysticercosis (NCC) develops after invasion of the brain by parasitic larvae. It is the most common parasitic disease of the human central nervous system.
View Article and Find Full Text PDFBackground: Neurocysticercosis (NCC) is a disease of the central nervous system (CNS) caused by the cestode Taenia solium. The infection exhibits a long asymptomatic phase, typically lasting 3 to 5 years, before the onset of the symptomatic phase. The severity of the symptoms is thought to be associated with the intensity of the inflammatory response elicited by the degenerating parasite.
View Article and Find Full Text PDF[Neurocysticercosis discovered incidentally during an asynchronous single brain metastasis of breast adenocarcinoma].
Rev Neurol (Paris)
January 2015
Centre Mohammed VI pour le traitement des cancers, CHU Ibn-Rochd, 4, rue d'Armenie avenue 2 mars, Casablanca, Maroc.
Concurrent neurocysticercosis and pulmonary tuberculosis.
Neurocrit Care
September 2009
Ronald Reagan UCLA Medical Center, 757 Westwood Plaza, Suite 6236 B, Los Angeles, CA 90095, USA.
Objective: We discuss the case of a 24-year-old male with severe racemose neurocysticercosis.
Clinical Features: The patient presented from an outside hospital with 4 months duration of intermittent syncope and a dull occipital headache with greatest severity in the morning. He was noted to have left facial numbness and blurred vision confined to his left eye.
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