Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and describe a number of single-nucleotide variations that correlate with its XDR phenotype.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192383PMC
http://dx.doi.org/10.1128/genomeA.01002-14DOI Listing

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