Lymphatic filariasis is a global health problem endemic in Nigeria. Peripheral blood smears are frequently negative for microfilariae in a significant number of infected patients in whom conventional diagnostic methods may also fail to identify the disease. In such cases, fine needle aspiration cytology may play an important role in disease identification. A 49-year-old South-western male Nigerian farmer, presented with a one-year history of a right groin swelling, which became painful 2 weeks before coming to the hospital. A clinical assessment of lymphogranuloma venereum was made to rule out a non-Hodgkin lymphoma. Initial laboratory investigations only showed mild eosinophilia and haematuria. However, fine needle aspiration cytology performed on the swelling showed microfilariae of Wuchereria bancrofti for which appropriate treatment was instituted with excellent outcome. This case demonstrates that lymphatic filariasis should be considered in the differential diagnosis of lymph node swellings in the groin and that aspiration cytology may play an important role in its diagnosis, especially in an endemic resource poor country.
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http://dx.doi.org/10.4103/0300-1652.140392 | DOI Listing |
Cancer Cytopathol
January 2025
Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
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View Article and Find Full Text PDFDiagn Cytopathol
December 2024
Department of Anatomic Pathology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Cytopathology is a cost-effective diagnostic method crucial for investigating suspected neoplastic lesions, particularly in Nigeria's healthcare system, where non-communicable diseases, especially with increasing rates of cancer. This review highlights the evolution of cytopathology practice in Nigeria, detailing its historical development, current methodologies, and the challenges faced within the healthcare framework. Despite advancements in diagnostic techniques such as immunocytochemistry and molecular diagnostics globally, conventional methods remain essential due to their affordability and accessibility.
View Article and Find Full Text PDFCytojournal
November 2024
Department of Pathology and Genomic Medicine, Houston Methodist, Houston, Texas, USA.
Objective: Diagnosing neoplasms of the salivary gland is challenging, as morphologic features of these tumors are complex, and well-defined diagnostic categories have overlapping features. Many salivary gland neoplasms are associated with recurrent genetic alterations. The utilization of RNA-based targeted next-generation sequencing (NGS) panels for the detection of cancer-driving translocations and mutations is emerging in the clinical laboratory.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
December 2024
West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Background: Non-obstructive azoospermia (NOA), the severe type of male infertility. The objective of this study was to evaluate the predictive accuracy of a prediction model of sperm retrieval failure with fine needle aspiration (FNA).
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J Cytol
November 2024
Department of Radiodiagnosis, Maulana Azad Medical College, New Delhi, India.
Background: Borderline ovarian tumors (BOTs) comprise 15%-20% of all ovarian epithelial malignancies. The majority of them are serous tumors followed by mucinous tumors. Pre-operative cytological diagnosis plays an important role with histopathology being the gold standard.
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