AI Article Synopsis
- The study examined the link between low maternal cholesterol levels in early pregnancy and the risk of preterm delivery.
- Researchers collected blood samples from pregnant women between 14-20 weeks gestation to measure cholesterol levels.
- Findings revealed that low maternal cholesterol significantly increased the likelihood of preterm birth, suggesting that maintaining healthy cholesterol levels through a balanced diet may be beneficial for pregnant women.
Article Abstract
Background: The study assessed whether low maternal serum cholesterol during early pregnancy is associated with preterm delivery.
Patients And Methods: It was a prospective observational cohort study involving pregnant women at gestational age of 14-20 weeks over a period of 12 months. Blood samples were obtained to measure total serum cholesterol concentrations and the sera were then analysed enzymatically by the cholesterol oxidase: p-aminophenazone (CHOD PAP) method.
Results: The study showed an incidence of 5.0% for preterm delivery in the low risk study patients. Preterm birth was 4.83-times more common with low total maternal cholesterol than with midrange total cholesterol (11.8% versus 2.2%, P = 0.024).
Conclusion: Low maternal serum cholesterol (hypocholesterolaemia) is associated with preterm delivery. Optimal maternal serum cholesterol during pregnancy may have merit, therefore pregnant women should be encouraged to follow a healthy, balanced diet.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178338 | PMC |
| http://dx.doi.org/10.4103/0300-1652.140381 | DOI Listing |
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