Factor XI deficiency diagnosed following use of adalimumab.

Indian J Pharmacol

Internal Medicine Clinic, Bezmialem Vakif University, Faculty of Medicine, Fatih, Istanbul, Turkey.

Published: June 2015

Adalimumab is a drug used in the treatment of refractory psoriasis. We present a case of a 55-year-old male patient who developed petechiae and purpura after the ninth dose of adalimumab therapy. The results of laboratory investigations revealed factor XI (F.XI) deficiency. It should be recognized that F XI deficiency may develop in patients using long-term adalimumab, leading to increased risk of bleeding.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175897PMC
http://dx.doi.org/10.4103/0253-7613.140596DOI Listing

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