DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.

Bioinformatics

Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK.

Published: February 2015

Summary: Gene duplication and loss are important processes in the evolution of gene families. Moreover, growth of families by duplication and retention is an important mechanism by which organisms gain new functions. Therefore the ability to infer the evolutionary histories of families is an important step in understanding the evolution of function. We have recently developed DupliPHY, a software tool to infer gene family histories using parsimony and maximum likelihood. Here, we present DupliPHY-Web a web server for DupliPHY that implements additional maximum likelihood functionality and provides users an intuitive interface to run DupliPHY.

Availability And Implementation: DupliPHY-Web is available at www.bioinf.manchester.ac.uk/dupliphy/

Contact: : ryan.ames@manchester.ac.uk

Supplementary Information: Supplementary data are available at Bioinformatics online.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308661PMC
http://dx.doi.org/10.1093/bioinformatics/btu645DOI Listing

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