We present the research advances on the development of 50-200 mJ energy range diode-pumped Yb:CaF2- based multipass amplifiers operating at relatively high repetition rates. These laser amplifiers are based on diverse innovative geometries. All these innovations aim to design compact, stable and reliable amplifiers adapted to our application that consists in pumping ultrashort-pulse OPCPA (optical parametric chirped pulse amplifier) systems in the frame of the Apollon 10 PW laser project. The targeted repetition rate is in the range of 20-100 Hz with energies of few tens of mJ for the first stages up to 1 J for the final stage. An analysis of the specificities of Yb:CaF2 is done to explain the different options we chose to fulfil these specifications. The critical points and limitations of the multipass Yb:CaF2-based amplifiers are subsequently discussed. To overcome the encountered problems, different issues are investigated such as crystal optimisation, laser head geometry, thermo-optical dynamics or coherent combining techniques. Experimental results for different multipass configurations are demonstrated and discussed.
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http://dx.doi.org/10.1109/TOH.2014.2330619 | DOI Listing |
J Family Med Prim Care
November 2024
Medical Student, College of Medicine, Qassim University, Al 'Qassim-Saudi Arabia.
Introduction: Colorectal cancer (CRC) has surged to prominence as the leading cancer affecting men and the second most common affecting women in Saudi Arabia. The need for preventative screening is underscored by the rising prevalence of precancerous polyps, early-stage colorectal cancer, and the fact that these conditions often manifest without symptoms.
Methods: This study utilized a cross-sectional descriptive design and employed data from a sample of 425 residents of Qassim region in Saudi Arabia.
Cureus
November 2024
Department of Radiology, Mito Kyodo General Hospital, Mito, JPN.
We report a case of an 87-year-old female with a ruptured hepatocellular carcinoma (HCC). She presented with sudden epigastric and right upper abdominal pain. The physical examination revealed mild tenderness in the right upper abdomen, a positive Murphy's sign, and no jaundice.
View Article and Find Full Text PDFInteract J Med Res
December 2024
Life Science Laboratories, KDDI research atelier, KDDI Research, Inc, Fujimino, Saitama, Japan.
Government policies in the United States and the European Union promote standardization and value creation in the use of FAIR (findability, accessibility, interoperability, and reusability) data, which can enhance trust in digital health systems and is crucial for their success. Trust is built through elements such as FAIR data access, interoperability, and improved communication, which are essential for fostering innovation in digital health technologies. This Viewpoint aims to report on exploratory research demonstrating the feasibility of testing a patient-centric data flow model facilitating semantic interoperability on precision medical information.
View Article and Find Full Text PDFPlant Foods Hum Nutr
December 2024
Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Subsede Sureste, Carretera Sierra Papacal-Chuburná Puerto - Parque Científico y Tecnológico de Yucatán. Tablaje Catastral 31264. Km 5.5, Mérida, México.
Crackers are bakery products that have shown an increase in consumption. One way to make crackers more nutritious is to add bioactive compounds, such as chia oil which is rich in polyunsaturated fatty acids. As these compounds are highly unsaturated, encapsulation techniques, such as nanoemulsion, allow the addition of them in foods, guaranteeing the preservation of their properties.
View Article and Find Full Text PDFGMS J Med Educ
December 2024
University of Halle-Wittenberg, Medical Faculty, Dorothea Erxleben Learning Centre, Halle (Saale), Germany.
Objective: The Halle continuum (HaKom) is a course for doctors undergoing postgraduate medical training in southern Saxony-Anhalt. It revises the skills and knowledge acquired during undergraduate medical training and develops them on an individual and needs-driven basis. The development and establishment of the three-day ready for (resident on-call) duty () course, which has been held four times a year since 2020, will be used as an example to present the overall HaKom curriculum.
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