In this perspective I look back on the twists and turns that influenced the direction of my scientific career over the past 40 years. From my early ambition to be a chemist to my training in Philadelphia and Bethesda as a molecular biologist, I benefited enormously from generous and valuable mentoring. In my independent career in Philadelphia and Princeton, I was motivated by a keen interest in the changes in gene expression that direct the development of the mammalian embryo and inspired by the creativity and energy of my students, fellows, and research staff. After twelve years as President of Princeton University, I have happily returned to the faculty of the Department of Molecular Biology.
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http://dx.doi.org/10.1146/annurev-cellbio-100913-013512 | DOI Listing |
J Orthop Case Rep
January 2025
Department of Trauma and Orthopaedic Surgeon, Cork University Hospital, Ireland.
Introduction: In this article, we report a unique case of head-stem dissociation in a metal-on-metal total hip replacement which utilized an Exeter stem. Although metallosis and pseudotumor formation are well recognized complications of metal-on-metal hip replacements, head-stem dissociations are rare with few being reported in literature. To the best of our knowledge, this case report is the first to report this occurrence in an Exeter stem.
View Article and Find Full Text PDFSociol Health Illn
January 2025
Department Public Health and Primary Care/Health Campus The Hague, Leiden University Medical Centre, The Hague, Netherlands.
Despite welfare state expansion in liberal democracies during the 20th century, health inequalities between socio-economic groups persist. Understanding individuals' lived experiences can inform policy for reducing unequal health outcomes in these lives. We build on Fundamental Cause Theory (FCT), which posits that low socio-economic status is the fundamental cause of health problems in (later) life.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Physics and Astronomy, California State University Northridge, Northridge, CA 91330-8268.
Moiré excitons and moiré magnetism are essential to semiconducting van der Waals magnets. In this work, we perform a comprehensive first-principles study to elucidate the interplay of electronic excitation and magnetism in twisted magnetic CrSBr bilayers. We predict a twist-induced quantum phase transition for interlayer magnetic coupling and estimate the critical twist angle below which moiré magnetism with mixed ferromagnetic and antiferromagnetic domains could emerge.
View Article and Find Full Text PDFNeth Heart J
December 2024
Department of Cardiology, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg.
Sci Robot
November 2024
School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, 1015, Switzerland.
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