AI Article Synopsis
- It can be tough to tell if someone is depressed because of their mind or because of a medical problem in their brain.
- A case study showed a patient's depression was caused by a serious brain tumor, not just typical depression.
- This highlights the need to look at the whole medical history and use brain scans to avoid mistakes when diagnosing depression.
Article Abstract
Objective: The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging.
Methods: We report a case with an initially typical severe depressive episode without any focal neurological deficits.
Results: Only medical history from a third party raised doubts about this provisional diagnosis. Brain magnetic resonance imaging revealed a highly malignant diffuse large intracerebral B-cell lymphoma in the right frontal lobe changing the diagnosis into an organic depressive disorder. The patient recovered after neurosurgical resection, chemotherapy and autologous stem cell transplantation.
Conclusion: This report helps to reduce possible errors in the differential diagnosis of depressive disorders by underlining the importance of a comprehensive medical history including anamnesis from a third party and neuroimaging, especially in first or atypical manifestation of depressive disorders.
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| http://dx.doi.org/10.1017/neu.2013.19 | DOI Listing |
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