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Coeliac disease: where are we in 2014? | LitMetric

Coeliac disease: where are we in 2014?

Aust Fam Physician

BMedSci, MB ChB, Dip Obs, FRNZCGP, senior lecturer and PhD candidate, Department of General Practice and Rural Health, Dunedin School of Medicine, University of Otago, Dunedin, NZ.

Published: October 2014

Background: Coeliac disease (CD) is an autoimmune condition affecting at least 1% of the population, many of whom remain undiagnosed. It is characterised by chronic inflammation of the small-intestinal mucosa and triggered by eating gluten. It is challenging to diagnose be-cause of the many and varied ways in which it may present.

Objective: To present up-to-date information on CD as we now understand it, with recommendations on whom to test and how to test them, and how to manage patients once they are diagnosed.

Discussion: Primary care practitioners have a crucial role in improving rates of CD diagnosis, and in the ongoing care of patients with CD. A blood test for coeliac-specific antibodies will identify most patients who need to undergo duodenal biopsy to make the diagnosis. Management encompasses supporting patients with adherence to the gluten-free diet and conducting a CD-focused clinical review every 1-2 years.

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