AI Article Synopsis
- The study evaluated the effectiveness and safety of transpupillary thermotherapy (TTT) for patients with choroidal indeterminate melanocytic lesions.
- Three treatment sessions were conducted on eight patients, with outcomes assessed related to lesion growth, visual acuity, and any complications.
- Results indicated high rates of lesion growth and serious visual loss associated with TTT, suggesting that while TTT was used, it did not adequately control these lesions and posed significant risks.
Article Abstract
Objective: This study aimed to assess the ocular and metastatic outcomes of patients with choroidal indeterminate melanocytic lesions treated by primary transpupillary thermotherapy (TTT).
Design: Retrospective case series.
Participants: Eight patients presenting choroidal indeterminate melanocytic lesions treated by primary TTT.
Methods: A retrospective chart review was conducted for patients with a newly diagnosed choroidal indeterminate melanocytic lesion treated by at least 3 TTT sessions from 2002 to 2011. Best-corrected visual acuity and lesion dimensions were measured at baseline and during follow-up. Complications were recorded including lesion growth, metastasis, melanoma-related mortality, and treatment-related complications.
Results: Mean initial thickness was 2.0 ± 0.8 mm. Patients had an average of 3.0 ± 0.9 risk factors for lesion growing. Three patients (38%) had lesion growth. Two patients (25%) had severe visual loss (>1.0 logMAR) directly related to TTT treatment. There were no fatalities due to metastasis.
Conclusions: Despite careful patient selection and systematic treatment with at least 3 TTT sessions, the use of primary TTT to treat patients with choroidal indeterminate melanocytic lesions with ≥ 1 risk factor for lesion growth yielded poor local lesion control and the possibility for severe ocular complications.
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| http://dx.doi.org/10.1016/j.jcjo.2014.07.011 | DOI Listing |
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