AI Article Synopsis
- Management of posttraumatic segmental bone loss from severe injuries is complex and often requires multiple surgical stages, with unpredictable outcomes and frequent complications.
- Reconstructive surgeons face challenges in treating these injuries, especially when initial treatments fail or lead to issues like pseudarthrosis.
- Biologic treatments have emerged to address some limitations of traditional methods by targeting specific bone healing processes.
Article Abstract
Management of posttraumatic segmental bone loss as a result of severe open injuries of the lower extremity, high-energy closed injuries, and following failed initial treatment of complex fractures that develop pseudarthrosis continues to challenge reconstructive surgeons. There are numerous strategies for dealing with such injuries but the outcome is unpredictable. The procedure is rarely only one stage and complications frequently arise. In most cases the reconstruction process is long and difficult and amputation must be part of the decision-making process. All traditional treatment strategies have advantages and major drawbacks. To overcome some limitations, biologic treatments have been developed based on specific pathways of bone physiology and healing.
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| http://dx.doi.org/10.1016/j.cpm.2014.06.008 | DOI Listing |
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