AI Article Synopsis
- The study aimed to evaluate the health and development of children who survived gastroschisis, focusing on their physical and metabolic outcomes at an average age of 9.
- Out of 50 children assessed, over half needed further surgeries, and many experienced abdominal pain, with some being hospitalized; however, most showed improvements in growth metrics.
- Children with complex gastroschisis had poorer growth outcomes compared to those with simple gastroschisis, and a notable percentage had elevated cholesterol levels and vitamin/mineral deficiencies, highlighting ongoing health challenges.
Article Abstract
Purpose: To determine the progress, physical and metabolic outcomes of gastroschisis survivors.
Methods: Fifty children born with gastroschisis were assessed with a health questionnaire, physical assessment, bone density and nutritional blood parameters at a median age of 9years (range 5-17).
Results: After initial abdominal closure, 27/50 (54%) required additional surgical interventions. Ten (20%) children had complex gastroschisis (CG). Abdominal pain was common: weekly in 41%; and requiring hospitalization in 30%. The weight, length and head circumference z-scores improved by a median 0.88 (p=0.001), 0.56 (p=0.006) and 0.74 (p=0.018) of a standard deviation (SD) respectively from birth; 24% were overweight or obese at follow up. However, those with CG had significantly lower median weight z-scores (-0.43 v 0.49, p=0.0004) and body mass index (BMI) (-0.48 v 0.42, p=0.001) at follow up compared to children with simple gastroschisis. Cholesterol levels were elevated in 24% of children. Bone mineral density was reassuring. There were 15 instances of low blood vitamin and mineral levels.
Conclusions: Although gastroschisis survival levels are high, many children have significant ongoing morbidity. Children with simple gastroschisis showed significant catch up growth and a quarter had become overweight.
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| http://dx.doi.org/10.1016/j.jpedsurg.2014.03.008 | DOI Listing |
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