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| http://dx.doi.org/10.1038/nature13691 | DOI Listing |
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The Lady and the Plants: Two Notions of Teleology in Agnes Arber's Philosophy of Plants.
J Hist Biol
January 2025
Ruhr University Bochum, Bochum, Germany.
Agnes Arber (1879-1960) was a British plant morphologist, historian of botany, and philosopher of biology. Though now largely forgotten, her work offers valuable insights into morphological as well as philosophical issues. This paper focuses on Arber's work on teleology in plants.
View Article and Find Full Text PDFInterpretable real-time monitoring of short-term rockbursts in underground spaces based on microseismic activities.
Sci Rep
January 2025
Department of Mining Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran.
In this study, two novel hybrid intelligent models were developed to evaluate the short-term rockburst using the random forest (RF) method and two meta-heuristic algorithms, whale optimization algorithm (WOA) and coati optimization algorithm (COA), for hyperparameter tuning. Real-time predictive models of this phenomenon were created using a database comprising 93 case histories, taking into account various microseismic parameters. The results indicated that the WOA achieved the highest overall performance in hyperparameter tuning for the RF model, outperforming the COA.
View Article and Find Full Text PDFInterpretable machine learning model for predicting clinically significant prostate cancer: integrating intratumoral and peritumoral radiomics with clinical and metabolic features.
BMC Med Imaging
December 2024
Department of MRI, Xinxiang Central Hospital (The Fourth Clinical College of Xinxiang Medical University), 56 Jinsui Road, Xinxiang, Henan, 453000, China.
Background: To develop and validate an interpretable machine learning model based on intratumoral and peritumoral radiomics combined with clinicoradiological features and metabolic information from magnetic resonance spectroscopy (MRS), to predict clinically significant prostate cancer (csPCa, Gleason score ≥ 3 + 4) and avoid unnecessary biopsies.
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Power Strokes in Molecular Motors: Predictive, Irrelevant, or Somewhere in Between?
J Am Chem Soc
January 2025
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.
For several decades, molecular motor directionality has been rationalized in terms of the free energy of molecular conformations visited before and after the motor takes a step, a so-called power stroke mechanism with analogues in macroscopic engines. Despite theoretical and experimental demonstrations of its flaws, the power stroke language is quite ingrained, and some communities still value power stroke intuition. By building a catalysis-driven motor into simulated numerical experiments, we here systematically report on how directionality responds when the motor is modified accordingly to power stroke intuition.
View Article and Find Full Text PDFNatural course of apparent diffusion coefficient (ADC) change after brain ischemic stroke: an alternative explanation by the triphasic relationship between T2 and ADC.
Quant Imaging Med Surg
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Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
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