Abstract: We present the case of a patient with multiple atraumatic osteoporotic vertebral fractures in an adolescent with suprasellar germinoma and also review of relevant literature. The patient suffered from a rare adolescent brain tumour with common complications which are often overlooked and give rise to significant morbidity. Suprasellar germinoma is an intracranial neoplasm, that in addition to its rarity, has variable clinical presentation. Despite appropriate treatment and good outcome, tumour related morbidity is still of concern for these patients.
Key Words: Secondary osteoporosis, suprasellar germinoma, panhypopituitarism.
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http://dx.doi.org/10.5704/MOJ.1207.007 | DOI Listing |
Cureus
November 2024
Neurosurgery, Jose R. Reyes Memorial Medical Center, Manila, PHL.
Germ cell tumors (GCTs) commonly develop in the pineal and suprasellar regions, with the most common GCTs being germinomas. In this report, a 22-year-old male presented with progressive right-sided weakness, and his imaging was consistent with a left thalamic high-grade glioma. A stereotactic biopsy was performed, revealing a germinoma, but radiation therapy was not done, and the patient was lost to follow-up.
View Article and Find Full Text PDFChilds Nerv Syst
December 2024
Department of Neuro-Intervention and Neuroradiology, National Institute of Mental Health & Neurosciences (NIMHANS), 29, Bengaluru, Karnataka, 560029, India.
J Cancer Res Ther
July 2024
Department of Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
An eight-year-old child presenting with increased thirst, raised intracranial tension and visual deterioration was diagnosed with synchronous suprasellar and pineal lesions, for which she underwent partial resection of the suprasellar lesion. Histopathological examination suggested pure germinoma. Tumor marker evaluation showed significantly raised levels of beta human chorionic gonadotropin (βHCG), favoring a non-germinoma germ cell tumor (NGGCT), leading to a diagnostic dilemma as the histology and βHCG levels were contradictory.
View Article and Find Full Text PDFRadiol Case Rep
December 2024
Department of Neuroradiology, Faculty of Medicine and Pharmacy, Specialty Hospital, University Hospital Center Ibn Sina, Abderrahim Bouabid Avenue, 10000, Rabat, Morocco.
Childs Nerv Syst
December 2024
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
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