Behavioral models of tinnitus and hyperacusis in animals.

Front Neurol

Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, University at Buffalo, The State University of New York, Buffalo, NY , USA.

Published: October 2014

The phantom perception of tinnitus and reduced sound-level tolerance associated with hyperacusis have a high comorbidity and can be debilitating conditions for which there are no widely accepted treatments. One factor limiting the development of treatments for tinnitus and hyperacusis is the lack of reliable animal behavioral models of these disorders. Therefore, the purpose of this review is to highlight the current animal models of tinnitus and hyperacusis, and to detail the advantages and disadvantages of each paradigm. To date, this is the first review to include models of both tinnitus and hyperacusis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166233PMC
http://dx.doi.org/10.3389/fneur.2014.00179DOI Listing

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