Foot ulceration due to neuropathy is a serious cause of morbidity in diabetes. Ulceration usually occurs at the part of the foot subjected to excessive mechanical pressure. A more generalized increase in pressure under the feet has also been shown to be a feature of many patients with diabetic neuropathy. In this study the electrodynogram was used to measure the pressure at seven positions under each foot. The maximum vertical foot bearing pressure was found to be higher in 11 diabetic patients with previously healed unilateral foot ulcers (10.6 +/- 5.9 kg cm-2) than in 11 diabetic patients who did not have such a history (4.2 +/- 1.3 kg cm-2). However there was no difference in pressure between the foot with previous ulceration and the contralateral foot (9.7 +/- 6.8 kg cm-2, 11.6 +/- 7.9 kg cm-2). Vertical foot bearing pressure was decreased by an average of 18% by wearing shoes padded with a Professional Protective Technology insole and the decrease was greater in patients with higher foot pressure. These results showed that increased vertical foot pressure is an important, but not the only, factor in determining the occurrence of foot ulcer.
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Nanomicro Lett
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Beijing Key Laboratory of Lignocellulosic Chemistry, College of Materials Science and Technology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
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Department of Chemical Engineering and Interdisciplinary Research Center for Hydrogen Technologies and Carbon Management (IRC-HTCM), King Fahd University of Petroleum and Minerals, 31261, Dhahran, Saudi Arabia.
Transition metal carbides, known as MXenes, particularly TiCT, have been extensively explored as promising materials for electrochemical reactions. However, transition metal carbonitride MXenes with high nitrogen content for electrochemical reactions are rarely reported. In this work, transition metal carbonitride MXenes incorporated with Pt-based electrocatalysts, ranging from single atoms to sub-nanometer dimensions, are explored for hydrogen evolution reaction (HER).
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Institute of Micro/Nano Materials and Devices, Ningbo University of Technology, Ningbo 315211, P. R. China.
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Department of Physics and Material Science, The University of Memphis, Memphis, Tennessee, 38152, USA.
Previously, we demonstrated the promise of aerogels for the repair of nerve injuries as neural cells extend longer processes (neurites) when grown on aerogels compared to a control surface. We also reported that the aerogel surface topography influenced neurite length. Neurite extension may be boosted by depositing collagen on the aerogel prior to plating the cells.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
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Jiangsu University, Institute for Energy Research, No. 301, Xuefu Road, 212013, Zhenjiang, CHINA.
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