Saliva-based biosensors: noninvasive monitoring tool for clinical diagnostics.

Biomed Res Int

Faculty of Biosciences and Medical Engineering (FBME), Universiti Teknologi Malaysia, Building VO1, Block A, Level 5, Room 27, 81310 Skudai, Johor, Malaysia.

Published: June 2015

Saliva is increasingly recognised as an attractive diagnostic fluid. The presence of various disease signalling salivary biomarkers that accurately reflect normal and disease states in humans and the sampling benefits compared to blood sampling are some of the reasons for this recognition. This explains the burgeoning research field in assay developments and technological advancements for the detection of various salivary biomarkers to improve clinical diagnosis, management, and treatment. This paper reviews the significance of salivary biomarkers for clinical diagnosis and therapeutic applications, with focus on the technologies and biosensing platforms that have been reported for screening these biomarkers.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172994PMC
http://dx.doi.org/10.1155/2014/962903DOI Listing

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