The influence of functional electrical stimulation on hand motor recovery in stroke patients: a review.

Exp Transl Stroke Med

Brain Imaging and Neurostimulation (BINS) Labor, Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg W34 20246, Germany ; Favaloro University Av, Belgrano 1746, Buenos Aires C1093AAS, Argentina.

Published: October 2014

Neuromuscular stimulation has been used as one potential rehabilitative treatment option to restore motor function and improve recovery in patients with paresis. Especially stroke patients who often regain only limited hand function would greatly benefit from a therapy that enhances recovery and restores movement. Multiple studies investigated the effect of functional electrical stimulation on hand paresis, the results however are inconsistent. Here we review the current literature on functional electrical stimulation on hand motor recovery in stroke patients. We discuss the impact of different parameters such as stage after stoke, degree of impairment, spasticity and treatment protocols on the functional outcome. Importantly, we outline the results from recent studies investigating the cortical effects elicited by functional electrical stimulation giving insights into the underlying mechanisms responsible for long-term treatment effects. Bringing together the findings from present research it becomes clear that both, treatment outcomes as well as the neurophysiologic mechanisms causing functional recovery, vary depending on patient characteristics. In order to develop unified treatment guidelines it is essential to conduct homogenous studies assessing the impact of different parameters on rehabilitative success.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178310PMC
http://dx.doi.org/10.1186/2040-7378-6-9DOI Listing

Publication Analysis

Top Keywords

functional electrical
16
electrical stimulation
16
stimulation hand
12
stroke patients
12
hand motor
8
motor recovery
8
recovery stroke
8
impact parameters
8
stimulation
5
recovery
5

Similar Publications

Tuberous Sclerosis Complex (TSC) is a debilitating developmental disorder characterized by a variety of clinical manifestations. While benign tumors in the heart, lungs, kidney, and brain are all hallmarks of the disease, the most severe symptoms of TSC are often neurological, including seizures, autism, psychiatric disorders, and intellectual disabilities. TSC is caused by loss of function mutations in the TSC1 or TSC2 genes and consequent dysregulation of signaling via mechanistic Target of Rapamycin Complex 1 (mTORC1).

View Article and Find Full Text PDF

Objectives: Ischemia/reperfusion (IR)-induced ventricular arrhythmia, which mainly occurs after the opening of coronary artery occlusion, poses a clinical problem. This study aims to investigate the effectiveness of pretreatment with coenzyme Q (CoQ) in combination with mitochondrial transplantation on IR-induced ventricular arrhythmias in aged rats.

Materials And Methods: Myocardial IR induction was performed by left anterior descending coronary artery occlusion for 30 min, followed by re-opening for 24 hr.

View Article and Find Full Text PDF

This study presents an innovative glucose detection platform, featuring a highly sensitive, non-enzymatic glucose sensor. The sensor integrates nickel nanowires and a graphene thin film deposited on the gate region of an extended-gate electric double-layer field-effect transistor (EGEDL-FET). This unique combination of materials and device structure enables superior glucose sensing performance.

View Article and Find Full Text PDF

Soft Artificial Synapse Electronics.

Research (Wash D C)

January 2025

Department of Electrical and Computer Engineering, University of Illinois, Urbana-Champaign, Urbana, IL 61801, USA.

Soft electronics, known for their bendable, stretchable, and flexible properties, are revolutionizing fields such as biomedical sensing, consumer electronics, and robotics. A primary challenge in this domain is achieving low power consumption, often hampered by the limitations of the conventional von Neumann architecture. In response, the development of soft artificial synapses (SASs) has gained substantial attention.

View Article and Find Full Text PDF

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats.

Bioact Mater

May 2025

Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Calle Sor Juana Inés de la Cruz 3, 28049, Madrid, Spain.

Millions of patients and their caretakers live and deal with the devastating consequences of spinal cord injury (SCI) worldwide. Despite outstanding advances in the field to both understand and tackle these pathologies, a cure for SCI patients, with their peculiar characteristics, is still a mirage. One of the most promising therapeutic strategies to date for these patients involves the use of epidural electrical stimulation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!