Aims: To evaluate the relation between residential distance and total ischaemic time in patients with acute ST-elevation myocardial infarction (STEMI).
Methods: STEMI patients were transported to the Isala Hospital Zwolle with the intention to perform primary percutaneous coronary intervention PCI (pPCI) from 2004 until 2010 (n = 4149). Of these, 1424 patients (34 %) were referred via a non-PCI 'spoke' centre ('spoke' patients) and 2725 patients (66 %) were referred via field triage in the ambulance (ambulance patients).
Results: A longer residential distance increased median total ischaemic time in 'spoke' patients (0-30 km: 228 min, >30-60 km: 235 min, >60-90 km: 264 min, p < 0.001), however not in ambulance patients (0-30 km: 179 min, >30-60 km: 175 min, >60-90 km: 186 min, p = 0.225). After multivariable linear regression analysis, in 'spoke' patients residential distance of >30-60 km compared with 0-30 km was not independently associated with ischaemic time; however, a residential distance of >60-90 km (exp (B) = 1.11, 95 % CI 1.01-1.12) compared with 0-30 km was independently related with ischaemic time. In ambulance patients, residential distance of >30-60 and >60-90 km compared with 0-30 km was not independently associated with ischaemic time.
Conclusion: A longer distance from the patient's residence to a PCI centre was associated with a small but significant increase in time to treatment in 'spoke' patients, however not in ambulance patients. Therefore, referral via field triage in the ambulance did not lead to a significant increase in time to treatment, especially at long distances (up to 90 km).
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http://dx.doi.org/10.1007/s12471-014-0599-8 | DOI Listing |
Nihon Koshu Eisei Zasshi
January 2025
Graduate School of Engineering Science, Osaka University.
Objectives Although childhood cancer treatment has recently become centralized at specialized hospitals worldwide, the relationship between mortality ratios and living in rural areas or traveling long distances for treatment remains controversial. In the present study, we examined whether regional differences in patient mobility and mortality ratios exist in Japan.Methods We investigated 10,713 patients with cancer aged ≤18 years, diagnosed between 2016 and 2019, registered in the national cancer registry data.
View Article and Find Full Text PDFEnviron Pollut
January 2025
Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. Electronic address:
PNPLA3-I148M genotype is the strongest predictive single-nucleotide polymorphism for liver fat. We examine whether PNPLA3-I148M modifies associations between oxidative gaseous air pollutant exposure (O) with i) liver fat and ii) multi-omics profiles of miRNAs and metabolites linked to liver fat. Participants were 69 young adults (17-22 years) from the Meta-AIR cohort.
View Article and Find Full Text PDFHeliyon
January 2025
Environmental Energy Technologies Laboratory (EETL), Department of Physics, University of Yaounde I, P.O Box 812 Yaounde, Cameroon.
This article analyzes and compares three methodologies for identifying suitable regions for solar hydrogen production using photovoltaic panels: AHP (Analytic Hierarchy Process), FAHP (Fuzzy Analytic Hierarchy Process), and MC-FAHP (Monte Carlo FAHP), integrated with GIS (Geographic Information Systems). The study employs ten criteria across technical (Global Horizontal Irradiance, temperature, slope, elevation, orientation), economic (distance from transportation and electrical networks), and social (population density, proximity to residential areas) factors. Environmental and exclusion criteria define restrictive zones.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Key Laboratory of Odor Pollution Control, Ministry of Ecology and Environment, Tianjin Academy of Eco-environmental Sciences, Tianjin 300191, China; Tianjin Sinodour Environmental Technology Co., Ltd., Tianjin 300191, China.
The rubber product manufacturing (RPM) industry generates a large number of odor complaints because persistent and distinctive volatile compounds are released during the associated processes. Such compounds represent a nuisance and may pose health risks to nearby residents. Extensive monitoring and sampling identified 146 volatile organic compounds (VOCs) from 20 enterprises across 6 subcategories of the RPM industry.
View Article and Find Full Text PDFMenopause
January 2025
Department of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA.
Objective: This study aimed to determine whether exposure to traffic-related air pollution (TRAP) is associated with depressive symptoms while also characterizing the contribution of key explanatory factors related to sociodemographics and health. In addition, it aimed to also explore the role of reproductive health as a pathway through which exposure to TRAP may relate to depressive symptoms.
Methods: Participants were 688 healthy reproductive-age women in the Ovarian Aging Study.
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