As monitoring of renal function, it is used the estimation of glomerular filtration rate (GFR). This study aimed to estimate the GFR by means of the Cockcroft-Gault equation in hypertensive patients in the Municipality of Vitoria-ES. It is a transversal study of secondary data with 754 hypertensive patients attended in health facilities in 2009. For statistical analysis, there has been used the chi-square test. The female sex, overweight and uncontrolled blood pressure predominated. The average age was 58.18 years (± 13.52) and the serum creatinine (SCr) 0.81 mg / dl (± 0.28). The prevalence of reduced GFR was 19% when from 30 to 59 ml/min and 1.6% when from 29 to 15 ml/min. The prevalence of reduced GFR was 15 times higher in the elderly, 4.93 times higher in those with elevated SCr, 2.19 times in low-weight hypertensives and 1.6 times more prevalent in men. The study showed the importance of monitoring renal function with a view to early intervention and postponement of kidney function loss in hypertensive patients.
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http://dx.doi.org/10.1590/0034-7167.2014670407 | DOI Listing |
BMC Cancer
January 2025
Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 West 5th Road, Xi'an, Shaanxi, 710004, China.
Background: Anthracycline usage has been linked to cardiovascular adverse events (CAEs), which is unpredictable. It is critical to identify the characteristics of vulnerable populations and risk factors in order to reduce the occurrence of CAEs.
Objectives: This meta-analysis aimed to assess the correlation between various risk factors and CAEs induced by anthracyclines.
BMC Infect Dis
January 2025
Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Introduction: Early antibiotic administration is one of the core treatments of sepsis which associated with reduced mortality rate. However, the appropriate timing of antibiotics remains a controversial issue, especially in patients without septic shock. Here, we reported the outcomes of early antibiotic administration within one hour from the time of infection suspicion in a tertiary care hospital.
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January 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Renal ischaemia due to renal artery stenosis produces two differing responses - a juxtaglomerular hypertensive response and cortical renal dysfunction. The reversibility of renal impairment is not predictable, and thus renal revascularisation is controversial. This study aims to test the hypothesis that the hypertensive response to renal ischaemia reflects viable renal parenchyma, and thus could be used to predict the recovery in renal function.
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January 2025
Clinical Department of Diabetology, Hypertension and Internal Diseases, Institute of Internal Diseases, Wroclaw Medical University, 213 Borowska St, Wroclaw, 50-556, Poland.
Oxidative stress is proven to increase cardiovascular risk and to diminish healthy life expectancy. Sleep bruxism (SB) is a prevalent masticatory muscle activity during sleep characterized by heterogeneous etiology and inadequately recognized pathophysiology. Recent theories have proposed a potential association between SB and oxidative stress.
View Article and Find Full Text PDFSteroids
January 2025
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address:
Background: 17α-Hydroxylase/17,20-lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia (CAH), caused by mutations in the CYP17A1 gene. It typically manifests clinically as variable degree of hypertension, hypokalemia, and disorders of sexual development (DSD), which can include abnormal sexual differentiation in males and sexual infantilism in females. Over 100 mutations in CYP17A1 have been identified, with most cases involving missense mutations or small deletions.
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