[Arrhythmia in patients with chronic heart insufficiency and type 2 diabetes mellitus].

Unlabelled: The aim of the work was to study character, frequency and peculiarities of arrhythmia in patients with chronic heart insufficiency (CHI) depending on its etiology and type 2 diabetes mellitus (DM2).

Materials And Methods: In-depth clinical observation of 197 patients (mean age 61.3 +/- 0.63 yr, 56-61% men) included EchoCG, 6 min walk test, Holter ECG monitoring. Group 1 was comprised of 74 patients with CHI (NYHA FC II), group of 280 patients with HPI an DM2, group 3 of 50 patients with CD2 (ADA criteria, 2011). The groups were matched for sex, age, severity of disease and complications. Exclusion criteria were acute coronary heart disease, CHI and DM2 decompensation, CHI according to BHOK and OCCH National recommendations (2009).

Results: 43.2% of the patients showed ventricular arrhythmia (VA) (p < 0.02), 10.8% had ciliary arrhythmia. Combined arrhythmia (ventricular and supraventricular arrhythmias, hemodynamically significant atrial fibrillation and high-grade ventricular arrhythmias) occurred in 41.2% of the patients having CHI+DM2 62.8% of the DM2 patients had supraventricular arrhythmias.

Conclusion: Hemodynamically and prognostically unfavourable arrhythmias are most frequently diagnosed in the patients with CHI and DM2 due to more pronounced myocardial failure and DM2-associated pathogenetic factors (dysglycemia, cardiac neuropathy, nephropathy).