The Trypanosoma cruzi clade is a group of parasites that comprises T. cruzi sensu lato and its closest relatives. Although several species have been confirmed phylogenetically to belong to this clade, it is uncertain how many more species can be expected to belong into this group. Here, we present the results of a survey of trypanosome parasites of the bat Artibeus jamaicensis from the Panamá Canal Zone, an important seed disperser. Using a genealogical species delimitation approach, the Poisson tree processes (PTP), we tentatively identified five species of trypanosomes - all belonging to the T. cruzi clade. A small monophyletic group of three putative Trypanosoma species places at the base of the clade phylogeny, providing evidence for at least five independent colonization events of these parasites into the New World. Artibeus jamaicensis presents a high diversity of these blood parasites and is the vertebrate with the highest number of putative trypanosome species reported from a single locality. Our results emphasize the need for continued efforts to survey mammalian trypanosomes.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182490 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108603 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Detecting complex infections in trypanosomatids using whole genome sequencing.
BMC Genomics
October 2024
York Biomedical Research Institute, Department of Biology and York Biomedical Research Institute, University of York, York, YO10 5DD, UK.
Background: Trypanosomatid parasites are a group of protozoans that cause devastating diseases that disproportionately affect developing countries. These protozoans have developed several mechanisms for adaptation to survive in the mammalian host, such as extensive expansion of multigene families enrolled in host-parasite interaction, adaptation to invade and modulate host cells, and the presence of aneuploidy and polyploidy. Two mechanisms might result in "complex" isolates, with more than two haplotypes being present in a single sample: multiplicity of infections (MOI) and polyploidy.
View Article and Find Full Text PDFClinical and epidemiological investigation of human infection with zoonotic parasite Trypanosoma dionisii in China.
J Infect
November 2024
State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing 100071, China. Electronic address:
Article Synopsis
- A 30-year-old pregnant woman in Shandong Province, China, was diagnosed with a persistent high fever, and high-throughput sequencing identified the presence of the parasite Trypanosoma dionisii in her blood.
- The patient showed symptoms like fever and respiratory issues but made a full recovery without long-term effects; genetic analysis revealed her infection was closely related to T. dionisii found in local bats.
- This case highlights T. dionisii as a potential zoonotic pathogen, emphasizing the risk of its transmission from wildlife, particularly rodents and bats, to humans.
Molecular detection of trypanosomes of the Trypanosoma livingstonei species group in diverse bat species in Central Cameroon.
Parasitol Res
July 2024
Department of Molecular Parasitology, Institute of Biology, Humboldt University, Berlin, Germany.
Bats are hosts for diverse Trypanosoma species, including trypanosomes of the Trypanosoma cruzi clade. This clade is believed to have originated in Africa and diversified in many lineages worldwide. In several geographical areas, including Cameroon, no data about trypanosomes of bats has been collected yet.
View Article and Find Full Text PDFMorphological and molecular characteristics of a Trypanosoma sp. from triatomines (Triatoma rubrofasciata) in China.
Parasit Vectors
May 2024
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, 200025, People's Republic of China.
Article Synopsis
- Triatomines (kissing bugs) are known carriers of trypanosomes, specifically in China, the transmission cycle of certain species like T. conorhini and Triatoma rubrofasciata is not well understood.
- Researchers conducted a study where they collected samples from Triatoma rubrofasciata to extract DNA and analyze it using microscopic and genetic methods, including sequencing and phylogenetic analysis.
- The results showed that Trypanosoma sp. present in the collected samples were closely related to T. conorhini, and laboratory tests indicated that these kissing bugs can transmit the parasite to rats and mice, albeit at low levels.
Phylogenetic description of Trypanosoma cruzi isolates from Dipetalogaster maxima: Occurrence of TcI, TcIV, and TcIV-USA.
Infect Genet Evol
September 2023
Facultad de Ciencias, Universidad Autonoma de Baja California, Carretera Transpeninsular Ensenada-Tijuana No. 3917, Colonia Playitas C.P. 22860, Ensenada, Baja California, Mexico.
Trypanosoma cruzi is the parasite responsible for Chagas disease. The parasite has been classified into six taxonomic assemblages: TcI-TcVI and TcBat (aka Discrete Typing Units or Near-Clades). No studies have focused on describing the genetic diversity of T.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!