AI Article Synopsis

  • - A solitary Peutz-Jeghers polyp is a unique polyp that occurs without related skin pigmentation or a family history, with very few cases (only eight) reported in gastric locations.
  • - The case study discusses a 43-year-old woman experiencing severe gastrointestinal symptoms, leading to the discovery of a large polyp during an endoscopy that appeared cancerous.
  • - After surgery and further analysis, the polyp was identified as a Peutz-Jeghers type, measuring 150/70/50 mm, marking it as the largest solitary gastric polyp of its kind documented and resembling a malignant tumor with lymph node involvement.

Article Abstract

A solitary Peutz-Jeghers polyp is defined as a unique polyp occurring without associated mucocutaneous pigmentation or a family history of Peutz-Jeghers syndrome. Gastric solitary localization is a rare event, with only eight reported cases to date. We report herein the case of a 43-year old woman who presented with upper gastrointestinal bleeding, severe anemia, weight loss and asthenia. Endoscopy revealed a giant polypoid tumor with signs of neoplastic invasion of the cardia, with pathological aspect suggesting a Peutz-Jeghers hamartomatous polyp. Computed tomography suggested a malignant gastric tumor and a total gastrectomy was performed. The pathological specimen showed a giant 150/70/50 mm polypoid tumor and immunochemistry established the final diagnostic of a Peutz-Jegers type polyp. This is the largest solitary Peutz-Jeghers gastric polyp reported until now, and the second one mimicking a gastric malignancy with lymph node metastasis.

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http://dx.doi.org/10.15403/jgld.2014.1121.233.vpb2DOI Listing

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