A solitary Peutz-Jeghers polyp is defined as a unique polyp occurring without associated mucocutaneous pigmentation or a family history of Peutz-Jeghers syndrome. Gastric solitary localization is a rare event, with only eight reported cases to date. We report herein the case of a 43-year old woman who presented with upper gastrointestinal bleeding, severe anemia, weight loss and asthenia. Endoscopy revealed a giant polypoid tumor with signs of neoplastic invasion of the cardia, with pathological aspect suggesting a Peutz-Jeghers hamartomatous polyp. Computed tomography suggested a malignant gastric tumor and a total gastrectomy was performed. The pathological specimen showed a giant 150/70/50 mm polypoid tumor and immunochemistry established the final diagnostic of a Peutz-Jegers type polyp. This is the largest solitary Peutz-Jeghers gastric polyp reported until now, and the second one mimicking a gastric malignancy with lymph node metastasis.
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http://dx.doi.org/10.15403/jgld.2014.1121.233.vpb2 | DOI Listing |
Rev Esp Enferm Dig
December 2024
Gastroenterology , The 980th Hospital of the People's Liberation Army.
A 24-year-old young female presented to our hospital with gastrointestinal bleeding for four days. The patient had no family history of polyps or cancer. There were no pigment spots on her skin, lips, or oral mucosa.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
National Academy of Medical Sciences, NAMS, Bir Hospital, Department of General Surgery, Kathmandu, Nepal.
Gastroenterology
January 2025
Division of Gastroenterology and Hepatology, Washington University School of Medicine, St. Louis, Missouri.
Description: Nonampullary duodenal polyps are found in up to 5% of all upper endoscopies; the vast majority are identified incidentally in asymptomatic patients. Although most are benign, adenomas are estimated to account for 10%-20% of these lesions. Most international guidelines recommend that all duodenal adenomas should be considered for endoscopic resection; this may be associated with a near 15% adverse event rate (predominantly bleeding and perforation) in prospective studies, with substantial local recurrence on surveillance.
View Article and Find Full Text PDFClin J Gastroenterol
November 2024
Department of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine, Aomori, 036-8562, Japan.
A solitary Peutz-Jeghers (PJ) polyp is a rare hamartomatous lesion without an associated PJ syndrome. However, little is known regarding malignancy arising in solitary PJ polyps. Here, we report a case of a solitary colonic PJ polyp with focal dysplasia.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
October 2024
Department of Digestive Nutrition, Hunan Children's Hospital, Changsha 410007, China.
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