This report describes an 18-year-old woman presenting with abdominal distension, left flank pain, and hypertension. She had a huge abdominal mass, diagnosed as a mesenteric desmoid-type fibromatosis, causing compression of the left external iliac vessels and ureter, as well as elevated renin concentration and hypertension. After surgical removal of the mass, all signs improved including hypertension.
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http://dx.doi.org/10.5468/ogs.2014.57.5.412 | DOI Listing |
Radiol Case Rep
February 2025
Department of Surgery « A », Ibn Sina Hospital, Mohammed V University, Faculty of Medicine and Pharmacy, Rabat, Morocco.
Desmoid tumors, also known as deep fibromatosis or desmoid-type fibromatosis, represent a rare subset of deep fibromatoses. It is a locally aggressive tumor, with no specific symptoms, and no metastatic potential. We report a case of a 38-year-old male patient with an abdominal mass.
View Article and Find Full Text PDFCureus
September 2024
General and Colorectal Surgery, Queen's Hospital Burton, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.
World J Gastrointest Oncol
August 2024
Department of Gastrointestinal and Anal Surgery, The Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China.
Asian J Surg
August 2024
The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Kunming City, Yunnan Province, China. Electronic address:
Cureus
March 2024
Laboratory Medicine and Pathology, University of Minnesota, MInneapolis, USA.
Most cases of desmoid-type fibromatosis (DTF) exhibit a mutation in APC or CTNNB1. We report a case of mesenteric DTF in which no mutation in APC or CTNNB1 was found, but a germline variant of uncertain significance (VUS) in RAD51C and a subclonal mutation in MYST3 were identified. Whether these genetic changes are important in DTF in this case, or whether genetically conventional DTF cells were present at a density below detection is unknown; it will be of interest to see results in further studies of wild-type APC/CTNNB1 cases.
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