Aim: To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita.
Method: Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques.
Results: Four dibenzocylooctadiene lignans were isolated from K. heteroclita. Their structures were identified as heteroclitin R (1), heteroclitin S (2), gonisin O (3), and schisanlignone A (4).
Conclusion: Heteroclitin R (1) and heteroclitin S (2) are new natural lignans.
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| http://dx.doi.org/10.1016/S1875-5364(14)60105-9 | DOI Listing |
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Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita.
Chin J Nat Med
September 2014
Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China.
Aim: To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita.
Method: Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques.
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