From December 2012 to May 2013, an outbreak occurred among urban wild carnivores from Berlin. We collected 97 free-ranging raccoons from the city area. PCR assays, histopathology and immunohistochemistry confirmed canine distemper virus (CDV) infection in 74 raccoons. Phylogenetic analysis of haemagglutinin gene fragments (1767 nucleotides) of CDV isolated from four raccoons showed close relation to CDV isolates from foxes from Germany and a domestic dog from Hungary; all belonging to the "Europe" lineage of CDV. These study results suggest an inter-species transmission of CDV as the origin for the outbreak among the raccoon population. Implications for domestic pets and suggested interspecies transmission between urban wildlife and raccoons are discussed. This is the first major outbreak of CDV amongst free-ranging raccoons in Europe.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetmic.2014.08.034DOI Listing

Publication Analysis

Top Keywords

canine distemper
8
interspecies transmission
8
free-ranging raccoons
8
raccoons
6
cdv
6
outbreak
4
distemper outbreak
4
outbreak raccoons
4
raccoons suggests
4
suggests pathogen
4

Similar Publications

Morbillivirus Canis Infection Induces Activation of Three Branches of Unfolded Protein Response, MAPK and Apoptosis.

Viruses

November 2024

Laboratorio de Virología, Centro de Microbiología Básica y Aplicada (CEMIBA), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata CP 1900, Buenos Aires, Argentina.

, commonly named Canine distemper virus (CDV), is a morbillivirus implicated in several signs in the family. In dogs (), common signs of infection include conjunctivitis, digital hyperkeratosis and neuropathologies. Even with vaccination, the canine distemper disease persists worldwide so the molecular pathways implicated in the infection processes have been an interesting and promising area in new therapeutic drugs research in recent years.

View Article and Find Full Text PDF

Canine distemper virus (CDV) can infect a wide range of mammalian carnivores and can cause severe illness and death. Domestic dogs may be an important source of this virus for endangered wild carnivores. The objective of this study was to establish the presence of CDV in rural areas of Cambodia bordering three established protected habitats, and to determine the seroprevalence of CDV in free-roaming dogs inhabiting these areas.

View Article and Find Full Text PDF

Expression and characterization of canine distemper virus hemagglutinin protein in suspension mammalian cells.

J Virol Methods

December 2024

Department of Viral Infectious Diseases of Special Animals, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, China; Jilin Provincial Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, China. Electronic address:

Hundreds of millions of the domestic dogs worldwide are routinely inoculated with the modified live vaccines for canine distemper virus (CDV) every year. However, the corresponding serological diagnostic and detections are always lacking, thus, there is an urgent demand to establish its unique diagnostic technologies to produce high-quality antigenic biomolecules. In the present study, the ectodomain (et) of CDV hemagglutinin (H) protein was firstly expressed in a soluble and secreted forms by an Expi293F transient transfection system based on its antigenic secondary structure analysis.

View Article and Find Full Text PDF

Molecular detection and quantification of canine parvovirus 2 using a fast and sensitive SYBR green-based quantitative polymerase chain reaction assay in dogs affected with gastroenteritis.

Vet World

October 2024

Facultad de Ciencias de la Salud, Carrera de Medicina Veterinaria, Universidad de Las Américas (UDLA), Quito, Ecuador, Antigua Vía a Nayón S/N, Quito EC 170124, Ecuador.

Background And Aim: Viral gastroenteritis in canines is primarily caused by the canine parvovirus 2 (CPV-2). Infections by this virus can cause severe consequences in dogs, such as fever, vomiting, diarrhea, septicemia, systemic inflammation, and immunosuppression. Therefore, the mortality rate of persistent infections caused by this virus is significantly high.

View Article and Find Full Text PDF
Article Synopsis
  • Invasive raccoons in Hokkaido, Japan, are potential carriers of the canine distemper virus, with a study analyzing 611 serum samples revealing higher infection rates in 2007, 2021, and 2022 compared to 2008-2012, indicating outbreak occurrences during those years.
  • Logistic regression showed that raccoon population density and environmental factors, like residential area ratios, were linked to seropositivity rates, particularly highlighting changes over the years from forest to residential areas.
  • Ongoing monitoring and improved raccoon control efforts are crucial to prevent disease spread to native wildlife like raccoon dogs and foxes, as well as to protect domestic dogs from health risks.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!