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A new HCV mouse model on the block. | LitMetric

A new HCV mouse model on the block.

Cell Res

1] Inserm, U1110, Strasbourg, France [2] Université de Strasbourg, Strasbourg, France [3] Pôle Hépato-digestif, Institut Hospitalo-Universitaire, Strasbourg, France.

Published: October 2014

The investigation of virus-induced liver disease and hepatocellular carcinoma needs small animal models modeling hepatitis C virus (HCV) infection and liver disease biology. A recent study published in Cell Research reports a novel mouse model which is permissive for chronic HCV infection and shows chronic liver injury including inflammation, steatosis and fibrosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185350PMC
http://dx.doi.org/10.1038/cr.2014.126DOI Listing

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