This study examined ionizing radiation-induced tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4) mRNA expression changes in human peripheral blood cells and their distribution in a normal population. The results showed that expression level of TNFSF4 mRNA exhibited a dose-dependent response after different irradiation doses, but that was independent of incubation time post-irradiation. Moreover, it was not affected by age and gender in 51 healthy donors. Our studies indicate that TNFSF4 can be considered as a candidate gene to develop a new biodosimeter.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3967/bes2014.107 | DOI Listing |
Publication Analysis
Top Keywords
expression changes
8
human peripheral
8
peripheral blood
8
tnfsf4 mrna
8
x-ray-induced expression
4
tnfsf4
4
changes tnfsf4
4
tnfsf4 gene
4
gene human
4
blood study
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!