Background & Objectives: Diagnosis of lymphatic filariasis using serum has been established but the utility of hydrocele fluid for the purpose is not exactly known. Since, hydrocele is a chronic form of the disease manifestation in a variety of situations and often poses difficulty in diagnosing its origin, we have evaluated the usefulness usage of hydrocele fluid for diagnosis of filarial origin of hydrocele in this study.
Methods: Paired samples of serum and hydrocele fluid from 51 individuals with hydrocele, living in an endemic area of Wuchereria bancrofti were assessed. Circulating filarial antigen, filarial specific antibody and cytokine assay were performed in both serum and hydrocele fluid of patients.
Results: Og4C3 assay detected circulating filarial antigen (CFA) in serum and corresponding hydrocele fluids. The level of IgG, IFN-γ and IL-10 were found to be high in CFA-negative, while IgM and IgE were high in CFApositive hydrocele fluid and serum samples associated with hydrocele. On the other hand neither CFA-positive nor CFA-negative hydrocele fluid and serum samples associated with hydrocele showed any difference in IgG4 level.
Interpretation & Conclusion: This study showed that the filaria related antigens and antibodies found in serum can be detected with equal sensitivity in hydrocele fluid. Therefore, it can be used as an alternative to serum for immunodiagnosis of filariasis, and help monitoring the filarisis elimination programme.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Canal of Nuck hydrocele in elderly female with cirrhosis: A case report and review of literature.
Med J Armed Forces India
December 2024
Professor (Surgery), Topiwala National Medical College, Mumbai, Maharashtra, India.
Hydrocele of the Canal of Nuck is a rare inguinal-scrotal swelling that occurs primarily as a chronic painful lump in childhood or in young women. Here, we present a rare case of the same, presenting at an extreme of age and with a short history. An 85-year-old female patient presented with a progressive inguinal swelling for 2 months in a known case of decompensated cirrhosis of liver in form of ascites and portal cavernoma.
View Article and Find Full Text PDFBilateral Patent Processus Vaginalis with Chylous Effusion in a Pediatric Patient: A Rare Case Report and Literature Review.
J Inflamm Res
November 2024
Pediatric Urology Department, Anhui Provincial Children's Hospital, Hefei, Anhui, People's Republic of China.
Background: Chylous effusion is a rare condition characterized by the accumulation of lymphatic fluid in body cavities, often due to trauma, malignancy, or congenital lymphatic abnormalities. The association of chylous effusion with a patent processus vaginalis (PV) in pediatric patients is exceptionally uncommon, presenting unique diagnostic and therapeutic challenges.
Objective: To report a rare case of bilateral patent processus vaginalis with chylous effusion in a pediatric patient, detailing the diagnostic process, surgical management, and outcomes, while contributing to the limited literature on this condition.
Clinical and hematological analysis of testicular torsion in children.
Front Pediatr
September 2024
The Second Department of Pediatric Urology Surgery, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University-Anhui Campus, Hefei, Anhui, China.
Purpose: Analyze the clinical manifestations, laboratory tests, and imaging data of testicular torsion to provide clinical insights for timely and accurate diagnosis and treatment of testicular torsion.
Methods: A retrospective analysis was conducted on the clinical data of 67 pediatric patients suspected of testicular torsion, admitted and subjected to surgical exploration from June 2018 to June 2023. Based on whether the torsed testicle was excised during surgery, the patients were divided into orchiectomy group (40 cases) and orchidopexy group (27 cases).
Hydrocele among Patients undergoing Surgery in the Department of Surgery in a Tertiary Care Center: A Descriptive Cross-sectional Study.
JNMA J Nepal Med Assoc
June 2024
B.P Smriti Hospital, Mahrajgunj, Kathmandu, Nepal.
Article Synopsis
- Hydrocele is a common condition involving fluid accumulation in the scrotum, leading to painless swelling, and has been minimally studied in Nepal.
- A year-long study analyzed medical records from a surgical department in a tertiary care center, identifying cases of hydrocele surgery and gathering data on prevalence and patient demographics.
- Findings revealed that out of 1812 surgeries, 95 were hydrocele-related, mainly non-communicating and unilateral; the majority of patients were around 50 years old, and 20% experienced postoperative complications.
Minimally invasive surgical approach for abdominoscrotal hydrocele treatment: A case report.
Curr Urol
September 2024
Department of Urology, L'Aquila University, Mazzini Hospital, Teramo, Italy.
Abdominoscrotal hydrocele (ASH) is a rare clinical finding comprising fluid collection between the layers of the tunica vaginalis, extending from the scrotum to the abdominal cavity. At present, there is no unique or recommended management for ASH, and different surgical treatments have been proposed. Despite an open surgical approach being the most common treatment, the use of laparoscopy has also previously been described.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!