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Restenosis after balloon valvuloplasty in a dog with pulmonary stenosis. | LitMetric

Restenosis after balloon valvuloplasty in a dog with pulmonary stenosis.

J Vet Med Sci

Laboratory of Surgery 1, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa 252-5201, Japan.

Published: January 2015

AI Article Synopsis

Article Abstract

A two-month-old female Chihuahua was diagnosed as severe pulmonary valvular stenosis (PS). Although balloon valvuloplasty (BV) was successfully performed, restenosis was observed 19 months after the procedure. Euthanasia was chosen due to low output syndrome during the surgical repair attempted when the dog was 5 years old. Postmortem examination revealed markedly thickened pulmonary valve due to the increase of extracellular matrix which might be produced by increased α smooth muscle actin-positive myofibroblasts. The thickening of the valve was associated with restriction of the valve's motion, resulting in restenosis in the present case. This is the first case report documented histopathological and immunohistochemical findings of the restenotic pulmonary valve in dogs with PS after BV.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349544PMC
http://dx.doi.org/10.1292/jvms.14-0242DOI Listing

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