The objective of this study was to examine whether factors such as insertion site, patient's facial pattern, microscrew features, type of tooth movement desired, level of experience handling orthodontic microscrews and operator expertise were associated with failure of microscrews. After the approval of an ethics committee, 166 patients of one practice signed an informed consent and received 293 microscrews randomly distributed by 3 operators with different levels of practical experience and expertise in handling microscrews. The microscrews were observed in a period of 365 days or as long as orthodontic forces had to be applied and independent variables were recorded. Analysis by the chi-square test did not produce enough evidence as to allow the assertion that there was an association between the variable "failure" and the variables "maxilla" (p=0.4775), "face" (p=0.1081), "facial pattern" (p=0.7522), "microscrew length" (p=0.9113), "desired movement" (p=0.0584), and "operator" (p=0.5785). The variable "insertion side" was significantly associated with "failure" (p=0.0022). In a 365-day survival analysis, the Log Rank test yielded a p-value of 0.00178 for the curve of variable "insertion side," and showed no significant differences for other variables. With a total success rate of 87.38%, the only variable found to be significant was "insertion side" (p=0.0022), with 3.088 more likelihood of a microscrew failing if placed on the left side than on the right side. The procedure of inserting microscrews involved a rapid learning curve for an inexperienced operator, which justifies their placement by orthodontists.
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http://dx.doi.org/10.1590/0103-6440201300125 | DOI Listing |
Clin Rev Allergy Immunol
January 2025
Postgraduate Program in Biochemistry, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brazil.
Asthma is a complex disease with varied clinical manifestations resulting from the interaction between environmental and genetic factors. While chronic airway inflammation and hyperresponsiveness are central features, the etiology of asthma is multifaceted, leading to a diversity of phenotypes and endotypes. Although most research into the genetics of asthma focused on the analysis of single nucleotide polymorphisms (SNPs), studies highlight the importance of structural variations, such as copy number variations (CNVs), in the inheritance of complex characteristics, but their role has not yet been fully elucidated in asthma.
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Department of Pediatric Anesthesia and Intensive Care, Necker-Enfants Malades University Hospital, AP-HP Centre, Université Paris Cité, 149, Rue de Sèvres 75015, Paris, France.
Retroperitoneal robotic-assisted laparoscopic pyeloplasty (R-RALP) is the commonest urologic procedure performed in children, entailing retroperitoneal CO2 insufflation and lateral decubitus, whose effects on cardiopulmonary variables are poorly known. We, therefore, studied hemodynamic and respiratory changes due to CO2 insufflation and lateral decubitus in children undergoing R-RALP and their effects on regional tissue oxygenation. Between 1/2021 and 7/2024, children affected by ureteropelvic joint obstruction (UPJO) underwent a pyeloplasty by R-RALP at Necker Enfants Malades Hospital (Paris, France), using a standardized surgical technique and a lung-protecting anesthetic protocol aimed to prevent hypercarbia.
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Department of Biomedical Engineering and the School of Brain Sciences and Cognition, Ben Gurion University of the Negev, Beer Sheva, Israel.
Background: Correct identification of the epidural space requires extensive training for technical proficiency. This study explores a novel bimanual haptic simulator designed for the precise insertion of an epidural needle based on loss-of-resistance (LOR) detection, providing realistic dual-hand force feedback.
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Ann Acad Med Singap
December 2024
Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
Introduction: Pleural infections are a significant cause of mortality. Intrapleural fibrinolytic therapy (IPFT) utilising alteplase and dornase is a treatment option for patients unsuitable for surgery. The optimal dose of alteplase is unknown, and factors affecting treatment success in an Asian population are unclear.
View Article and Find Full Text PDFJ Pediatr Surg
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Golisano Children's Hospital, Rochester, NY, USA.
Background: Gastrostomy tube (GT) placement is one of the most common procedures performed by pediatric surgeons; however, no current national clinical data registry exists to assess GT-specific care processes and morbidity. The American College of Surgeons (ACS) National Surgical Quality Improvement Program-Pediatric (NSQIPPed) GT Pilot was created to provide participants with these data. This study aims to analyze these data to identify variability in perioperative practices and post-operative morbidity in pediatric GT operations and to provide targets for future quality improvement (QI) interventions.
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