AI Article Synopsis
- Rabbit hemorrhagic disease virus (RHDV) is a deadly virus that primarily threatens European rabbits but has also been shown to infect some hares.
- Recent research identified two strains of RHDV from dead Iberian hares in Portugal, indicating that the virus can infect species beyond its usual host.
- The study's phylogenetic analysis suggests these strains are part of the RHDV genogroup that was present in the Iberian Peninsula in the 1990s, marking the earliest known case of RHDV affecting a non-rabbit species.
Article Abstract
Rabbit hemorrhagic disease virus (RHDV) is a highly lethal Lagovirus, family Caliciviridae, that threatens European rabbits (Oryctolagus cuniculus). Although a related virus severely affects hares, cross-species infection was only recently described for new variant RHDV in Cape hares (Lepus capensis mediterraneus). We sequenced two strains from dead Iberian hares (Lepus granatensis) collected in the 1990s in Portugal. Clinical signs were compatible with a Lagovirus infection. Phylogenetic analysis of the complete capsid gene positioned them in the RHDV genogroup that circulated on the Iberian Peninsula at that time. This is the earliest evidence of RHDV affecting a species other than European rabbits.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189657 | PMC |
| http://dx.doi.org/10.1186/s13567-014-0094-7 | DOI Listing |
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