In scattering media, as in underwater or haze and fog in atmosphere, image contrast deteriorates significantly due to backscatter. This adversely affects the performance of many computer vision techniques developed for clear open-air conditions, including stereo matching, when applied to images acquired in these environments. Since the strength of the scattering depends on the distance to the scene points, the scattering field embodies range information that can be exploited for 3-D reconstruction. In this paper, we present an integrated solution for 3-D structure from stereovision that incorporates the visual cues from both disparity and scattering. The method applies to images of scenes illuminated by artificial sources and natural lighting, and performance improves with discrepancy between the backscatter fields in the two views. Neither source calibration nor knowledge of medium optical properties is required. Instead, backscatter fields at infinity, i.e., stereo images taken with no target in the field of view, are directly employed in the estimation process. Results from experiments with synthetic and real data demonstrate the key advantages of our method.
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Nat Commun
January 2025
Tulane Center for Biomedical Informatics and Genomics, Deming Department of Medicine, School of Medicine, Tulane University, New Orleans, LA, 70112, USA.
Aging increases the risk for Alzheimer's disease (AD), driving pathological changes like amyloid-β (Aβ) buildup, inflammation, and oxidative stress, especially in the prefrontal cortex (PFC). We present the first subcellular-resolution spatial transcriptome atlas of the human prefrontal cortex (PFC), generated with Stereo-seq from six male AD cases at varying neuropathological stages and six age-matched male controls. Our analyses revealed distinct transcriptional alterations across PFC layers, highlighted disruptions in laminar structure, and exposed AD-related shifts in layer-to-layer and cell-cell interactions.
View Article and Find Full Text PDFEpilepsia
January 2025
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Objective: Somatic variants causing epilepsy are challenging to detect, as they are only present in a subset of brain cells (e.g., mosaic), resulting in low variant allele frequencies.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
We report a stereo-differentiating dynamic kinetic asymmetric Rh(I)-catalyzed Pauson-Khand reaction, which provides access to an array of thapsigargin stereoisomers. Using catalyst-control, a consistent stereochemical outcome is achieved at C2─for both matched and mismatched cases─regardless of the allene-yne C8 stereochemistry. The stereochemical configuration for all stereoisomers was assigned by comparing experimental vibrational circular dichroism (VCD) and C NMR to DFT-computed spectra.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Information and Communication Engineering, Korea University of Technology and Education (KOREATECH), Cheonan-si 31253, Republic of Korea.
This paper presents a novel method to enhance ground truth disparity maps generated by Semi-Global Matching (SGM) using Maximum a Posteriori (MAP) estimation. SGM, while not producing visually appealing outputs like neural networks, offers high disparity accuracy in valid regions and avoids the generalization issues often encountered with neural network-based disparity estimation. However, SGM struggles with occlusions and textureless areas, leading to invalid disparity values.
View Article and Find Full Text PDFStrabismus
December 2024
Clinical Vision Science Program, Faculty of Health, Dalhousie University, Halifax, Canada.
: There remains a lack of compelling objective evidence on whether stereopsis is necessary for an ophthalmic surgical career. It is also unclear if high-grade stereoacuity correlates with better surgical performance. The present study attempts to address this question by comparing the simulated surgical performance of subjects with different levels of stereoacuity using a virtual reality (VR) intraocular surgical simulator (EYESi, VRmagic, Mannheim, Germany).
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