Disorders associated with back pain usually have two components. One pertains to the spinal disorder and the other to symptoms and signs that result from compromise of individual nerve roots, the cauda equina, or, in some cases, the conus medullaris. In this article, those spinal structures capable of giving rise to pain, its approximate distribution, the nature of the discomfort and disturbance of spinal and neural function consequent upon disease of the vertebral column, and the evaluation and management of the individual patient will be considered.
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Hepatology
January 2025
Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Carl-Neuberg Str. 1, 30625 Hannover, Germany.
Background Aims: Bulevirtide (BLV) is a novel and the only approved treatment option for patients with chronic hepatitis D (CHD). BLV alleviates liver inflammation already early during treatment when only minor HDV RNA changes are observed. We hypothesized that BLV-treatment may influence immune cells in CHD patients and performed a high-resolution analysis of natural killer (NK) cells before and during BLV-therapy.
View Article and Find Full Text PDFIr J Med Sci
January 2025
Sligo University Hospital, Sligo, Ireland.
Background: Chronic infection with hepatitis B virus and HIV causes significant morbidity and mortality. Effective antiviral treatment is available for both. Ireland has historically been considered a low prevalence country.
View Article and Find Full Text PDFSchmerz
January 2025
Neurologische Klinik und Poliklinik, LMU Klinikum, Ludwig-Maximilians-Universität München, Marchioninistraße 15, 81377, München, Deutschland.
Cluster headache is a severe primary headache disorder, which can be associated with a substantial impairment for sufferers. The Cluster Headache Impact Questionnaire (CHIQ) is a short questionnaire for measuring the cluster headache-specific impairment. A 5-stage severity grading from "no to low impairment" to "'extreme impairment" was established based on the results of an English-speaking patient collective.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Faculty of Dentistry, Ain Shams University, Organization of African Unity Street, Cairo, Egypt, 11766.
As photobiomodulation is growing in the dental field the aim of this prospective, two-arm clinical trial was to assess the radiographic changes for chronic periapical bone lesions related to mandibular molars after primary root canal therapy with or without applying Diode laser on soft tissue. The samples were randomly divided into a Laser group and a mock laser (ML) group. Preoperative CBCT images were compared 12 months later with postoperative CBCT to gauge the changes in the volume of the bony lesion by two observers.
View Article and Find Full Text PDFInt Arch Occup Environ Health
January 2025
Department of Physical Medicine and Rehabilitation, Lariboisière- Fernand Widal Hospital, Université Paris Cité, Assistance Publique- Hôpitaux de Paris, Paris, France.
Purpose: Little is known about the relationship between conflict at work and incident chronic low back pain (CLBP). Thus, this retrospective cohort study analyzed the association between conflict at work and the five-year incidence of CLBP in adults living in Germany.
Methods: This study included individuals aged 18-65 years reporting conflict at work for the first time in one of 1,293 general practices in Germany between 2005 and 2022 (index date).
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