Objective: Research on substance abusers in treatment suggests that tapentadol, a prescription analgesic, may have relatively low abuse potential. Messages posted by recreational drug abusers on online forums were examined for amount of discussion and endorsement for abuse of tapentadol and comparator drugs.
Methods: Internet messages posted between January 1, 2011 and September 30, 2012 on seven drug-abuse web forums were evaluated. Proportions of posts and unique authors discussing tapentadol were compared with eight comparator compounds. Postcontent was coded to compare endorsement for abuse of tapentadol with two comparators, one drug with high desirability for abuse and one with low desirability for abuse.
Results: A total of 1,940,121 messages posted during the study period were copied from selected web forums. The proportion of all posts discussing tapentadol (proportion = 0.0003) was significantly lower than any of the comparator compounds (range of odds ratios from 16.6 to 104.3; P < 0.001). The proportion of unique authors was also lower. Posts coded for endorsement (N = 2,117) yielded an endorsement ratio (Ero) of 2.14 for tapentadol, which was significantly lower than the highly desirable for abuse oxymorphone (ERo = 5.08; P = 0.0011) and was as low as tramadol (ERo = 1.66), which has a long-established profile of low abuse and desirability for abuse.
Conclusions: Recreational abusers posting on web forums appear to be less interested in abusing tapentadol when compared with other, selected prescription analgesics based on the amount of discussion (i.e., fewer posts and authors mentioning tapentadol). Endorsement of the product for abuse was also low.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/pme.12547 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An Efficient Cluster-Based Mutual Authentication and Key Update Protocol for Secure Internet of Vehicles in 5G Sensor Networks.
Sensors (Basel)
January 2025
School of Communication and Information Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210003, China.
The Internet of Vehicles (IoV), a key component of smart transportation systems, leverages 5G communication for low-latency data transmission, facilitating real-time interactions between vehicles, roadside units (RSUs), and sensor networks. However, the open nature of 5G communication channels exposes IoV systems to significant security threats, such as eavesdropping, replay attacks, and message tampering. To address these challenges, this paper proposes the Efficient Cluster-based Mutual Authentication and Key Update Protocol (ECAUP) designed to secure IoV systems within 5G-enabled sensor networks.
View Article and Find Full Text PDFUnraveling the Use of Disinformation Hashtags by Social Bots During the COVID-19 Pandemic: Social Networks Analysis.
JMIR Infodemiology
January 2025
Computational Social Science DataLab, University Institute of Research for Sustainable Social Development (INDESS), University of Cadiz, Jerez de la Frontera, Spain.
Background: During the COVID-19 pandemic, social media platforms have been a venue for the exchange of messages, including those related to fake news. There are also accounts programmed to disseminate and amplify specific messages, which can affect individual decision-making and present new challenges for public health.
Objective: This study aimed to analyze how social bots use hashtags compared to human users on topics related to misinformation during the outbreak of the COVID-19 pandemic.
Health promotion campaigns using social media: association rules mining and co-occurrence network analysis of Twitter hashtags.
BMC Public Health
January 2025
Victoria University, Institute for Health and Sport and Australian Health Policy Collaboration, Melbourne, Australia.
Background: Social media hashtags play a significant role in increasing the visibility of health information by making it easier for people to explore health-related content. Health promotion campaigns use campaign-specific hashtags to disseminate health-related messages, enabling individuals to access accurate and timely resources and updates. The study aims to discover patterns of connection between hashtags and identify the most influential hashtags used on Twitter in the American Heart Month campaigns.
View Article and Find Full Text PDFConcerns Over Vuse e-Cigarette Digital Marketing and Implications for Public Health Regulation: Content Analysis.
JMIR Form Res
December 2024
REACH Lab, Department of Pediatrics, Division of Adolescent Medicine, Stanford University, Palo Alto, CA, United States.
Background: Electronic cigarettes (e-cigarettes) are the most used form of tobacco products among adolescents and young adults, and Vuse is one of the most popular brands of e-cigarettes among US adolescents. In October 2021, Vuse Solo became the first e-cigarette brand to receive marketing granted orders (MGOs) from the US Food and Drug Administration (FDA), authorizing its marketing and their tobacco-flavored pods. Vuse Ciro and Vuse Vibe, and their tobacco-only ("original") e-liquids, were authorized for marketing in May 2022 and Vuse Alto tobacco-flavored devices were authorized in July 2024.
View Article and Find Full Text PDFPerspectives surrounding robotic total hip arthroplasty: a cross-sectional analysis using natural language processing.
Can J Surg
January 2025
From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Levett); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Elkaim); the Department of Orthopaedic Surgery, McGill University, Jewish General Hospital, Montréal, Que. (Zukor, Huk, Antoniou)
Article Synopsis
- The study analyzed social media discussions about robotic total hip arthroplasty (THA) to understand public perspectives and sentiments.
- A total of 742 tweets were collected, with most focused on raising awareness, advertisements, and personal experiences, showing a generally positive tone.
- Key findings suggested that orthopedic surgeons can utilize social media for insights into patient views and advancements in robotic surgery.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!